DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mbl and mbnl3

DIOPT Version :9

Sequence 1:	NP_001261046.1	Gene:	mbl / 36945	FlyBaseID:	FBgn0265487	Length:	956	Species:	Drosophila melanogaster
Sequence 2:	XP_012824887.2	Gene:	mbnl3 / 100496456	XenbaseID:	XB-GENE-999434	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	450	Identity:	165/450 - (36%)
Similarity:	219/450 - (48%)	Gaps:	129/450 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIK--------------- 63
            :|::||.|||||||||..|||.|.|||||||..:..|:||:|.||:||:|
Frog     9 RDTKWLTLEVCREFQRGTCSRSDAECKFAHPSRSCHVENGRVIACFDSLKIPSYSSFTPYIDGEL 73

  Fly    64 -------------GRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNA----LMQQMG-IAPG- 109
                         |||.|:.  |||.|||.|||.||.|||||:|..:..    |.|||. :.||
Frog    74 MYWNISLIPRNSIGRCTREN--CKYLHPPPHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMLPGT 136

  Fly   110 --QPVISGQV-PAVATNPYLTGIPANSYSPYYTTGH------LVPALLGPD-PVTSQLGPVVPQT 164
              ||:.:..| |::||:|.:      ::|||.:  |      ||||.|.|: ||.....|.|...
Frog   137 QLQPITTFPVTPSLATSPSM------AFSPYLS--HVSPGMGLVPAELLPNTPVLVSGNPAVTVP 193

  Fly   165 VQVAQQKIPRSDRLEVCREFLRGACKRAESECRFAHPQESVARHD--DGSITVCMDAVKGRCARD 227
            ...|.||:.|:|:|||||||.||.|.|.|::||:|||.: :|..|  :.::|||||.:||||:|:
Frog   194 GGSAGQKLVRTDKLEVCREFQRGNCTRGENDCRYAHPID-IAMIDTNENTVTVCMDYIKGRCSRE 257

  Fly   228 PCRYFHPPLHLQAQLKAAQTRATAVAAAAAVWLYTIYFSILFEPSLCMDVKTVGSFYYD-NFQFS 291
            .|:|||||.||||::||||.:....||||           :.:|:: ..:|.......| ..|..
Frog   258 KCKYFHPPAHLQAKIKAAQHQVNQTAAAA-----------MIQPAV-RSLKRPHKATLDLALQPG 310

  Fly   292 GMVPF-KRPAAEKS--GIPVYQPGATAYQQLMQPYVPVSCEYPQQQQQPPPQQQQQQQHQQQNVL 353
            .:.|. ||||.|||  ...|:.|....|||                                 .|
Frog   311 ALQPLPKRPALEKSNGATTVFNPSVFHYQQ---------------------------------AL 342

  Fly   354 LQQQLQLSSVITT-------TSTTATASNNMINNNINNKGIINAVMASTNITSSATTTAS 406
            ...|||..:.|.|       |.||.:|                |...:|::..:||.||:
Frog   343 ANMQLQQPTFIPTVPMMHGATPTTVSA----------------ATTPATSVPFAATATAN 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbl	NP_001261046.1	ZnF_C3H1	175..201	CDD:214632	16/25 (64%)
mbnl3	XP_012824887.2	ZnF_C3H1	17..39	CDD:214632	17/21 (81%)
mbnl3	XP_012824887.2	ZnF_C3H1	206..230	CDD:214632	15/23 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H23101
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4320
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001679
OrthoInspector	1	1.000	-	-		otm48120
Panther	1	1.100	-	-	O	PTHR12675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1238
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060