Protein Alignment CG10950 and KAP122

DIOPT Version :9

• Sequence 1: NP_611200.2
• Gene: CG10950 / 36942
• FlyBaseID: FBgn0034205
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_011499.1
• Gene: KAP122 / 852868
• SGDID: S000002984
• Length: 1081
• Species: Saccharomyces cerevisiae
• Alignment Length: 831
• Identity: 154/831 - (18%)
• Similarity: 267/831 - (32%)
• Gaps: 355/831 - (42%)

  Fly    41 IAEEILSYRPPHDMHILTFAAMSLAKKIKTSFYSLQKF-QLMSLKNSLIDHLKYAAMMRDSNSLI 104
            :.||:.|..|.||::           :|:.|..|:||. |...|.|.|:...||:|.::...:|
Yeast    10 LIEELYSPHPKHDVN-----------QIQQSLQSIQKSEQGFHLANELLSDDKYSANVKYFGAL- 62

  Fly   105 VQLAVGISALGLMFSQWDYE------------LQDFVRKLSENP-QYVMALLEVLK--------- 147
             .|.|.::..|    :.|||            |..|......|| .|..:|:.:.|
Yeast    63 -TLTVQLNTRG----ENDYETLWNVFRSNLLYLTKFSTLYVSNPNMYGQSLIIIKKLMSNLSLIF 122

  Fly   148 ---------------VIPEETRPSN-----LPVEAKKLNS---VID------TLEQQSPYILDVL 183
                           :|.:...|.|     :.|:.:.:|:   ::|      |.||.|.::
Yeast   123 TKINDPQLNNAGNENMIKQWNNPINTFIQLMSVQNQNINADQLLLDSINCSLTYEQLSQFV---- 183

  Fly   184 EGLLQRPDLPDDALPKCLAVCASWTKF-----SMLSPDQVLQRKLFI--MA-------------- 227
             .|.|:.:  :.||.....:....|||     ||....:|:...|:|  ||
Yeast   184 -SLSQKHN--ELALTFTEVIVEDLTKFQTKRHSMSQIHEVVHEHLYISTMALINLNLTAQAVFNP 245

  Fly   228 ----------EFILATPLV--NGHLEAAELF---VALLEQS------------------------ 253
                      .:|..|..|  :|.::.:|:|   :.|:.||
Yeast   246 TVFDCITAWINYISLTRSVSSSGRMDLSEIFQNLIDLMYQSTEGSDGYENAEKILTIFGNVFAND 310

  Fly   254 ------------------LIR-------------------------------KELNSCLANSV-- 267
                              ::|                               |||..|:.:.:
Yeast   311 PLLMSYDLRQQIECIFLGVVRPDSGITDISNKNSWMLQYMNYLVTNDFFSELKELAICIVDFLQI 375

  Fly   268 ----ICLK-----PAFKRSMGERSLLQNYCNIFVNLFQTHFRLTQTNPERLNERLVTIELLLLVA 323
                :|.|     .|......:...:|.|..:.:.:  |:|.||....|..:.|:|...|.|..|
Yeast   376 NTLSVCNKLFTNIQAADNGQVQDEYIQEYIKVLLQM--TNFPLTPVLQEFFSVRMVDFWLDLSDA 438

  Fly   324 EESPLEVIEASLGMWSSISEEVYLHDDPEMYSVYQPYFVRLLDLLLPRAALPANYEFMMPPGSA- 387
                          :::::.|..   .|....:....|.:|:::.||:.:|......:...|.:
Yeast   439 --------------YTNLASETL---RPNSIELSTQIFQQLINIYLPKISLSVKQRIIEEEGEST 486

  Fly   388 ---DMQRFRELIGE----------------VLLD-MAHM--IDDDT-----------VEKLC--- 416
               :.:.||..:.:                ||:| |..|  ..|:|           :|.:|
Yeast   487 SVNEFEDFRNAVSDLAQSLWSILGNDNLTNVLIDGMGQMPAASDETLIIKDTDVLFRIETMCFVL 551

  Fly   417 -SIVVD---EQSPWME--VEASVFFLRHLIGNFKE-HQTDI---ISCILKTFFQKDC-------- 463
             :|:||   .:|||::  |:|:.||.:::|..|:. .||..   :|.|||..|.:..
Yeast   552 NTILVDMTLSESPWIKNIVDANKFFNQNVISVFQTGFQTSASTKVSQILKLDFVRTSTTLIGTLA 616

  Fly   464 ----QQPFIRLQVLEL------------------------ISIPEIVSVETIWDCLVNELRRADP 500
                |:||.....:|.                        :.:..|.:|.|:.:....||   .|
Yeast   617 GYFKQEPFQLNPYVEALFQGLHTCTNFTSKNEQEKISNDKLEVMVIKTVSTLCETCREEL---TP 678

  Fly   501 MLSAIDCRLN-LLMPHWN------------------------------YLVTLAIMVD---EFCL 531
            .|......|| ::||..|                              |::.|..::.   |.||
Yeast   679 YLMHFISFLNTVIMPDSNVSHFTRTKLVRSIGYVVQCQVSNGPEEQAKYILQLTNLLSGSIEHCL 743

  Fly   532 KESERCE-----LLCSICTLIRELPAACVQEAKTSILNIRWIKCPAHIEEN 577
            ..|.:.:     :.|.:         .|:.|..||::.      |..|.||
Yeast   744 ASSVQLQEQQDYINCLL---------YCISELATSLIQ------PTEIIEN 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10950	NP_611200.2	IBN_N	25..91	CDD:197981	15/50 (30%)
		Xpo1	103..>207	CDD:285575	28/154 (18%)
KAP122	NP_011499.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12363
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100