Protein Alignment CG10950 and Tnpo-SR

DIOPT Version :9

• Sequence 1: NP_611200.2
• Gene: CG10950 / 36942
• FlyBaseID: FBgn0034205
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001259961.1
• Gene: Tnpo-SR / 33465
• FlyBaseID: FBgn0031456
• Length: 932
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 139/597 - (23%)
• Similarity: 275/597 - (46%)
• Gaps: 41/597 - (6%)

  Fly     5 FTKELVIDAVNMLSSGN----ISLANEYLAAFQKSNDTWIIAEEILSYRPPHDMHILTFAAMSLA 65
            ::.::|..|::.|..||    ...||::|..||||..:|.||:|:|..:  .|:|...|||.::.
  Fly     4 YSVDVVYQAISALFQGNNPKEQEKANKWLQDFQKSIYSWTIADELLHQK--RDLHANYFAAQTMR 66

  Fly    66 KKIKTSFYSLQKFQLMSLKNSLIDHLKYAAMMRDSNSLIVQLAVGISALGLMFSQWDYELQDFVR 130
            .||:.||..|......||::|||.|:.......| |.::.||::.::.|.|:.:.|...:.|.:.
  Fly    67 NKIQNSFSELPPHTHESLRDSLITHIGQIDEQTD-NVIVTQLSLAVADLALLMASWREPINDLLV 130

  Fly   131 KLSENPQYVMALLEVLKVIPEETRPSNLPVEAKKLNSVIDTLEQQSPYILDVLEGLLQRPDLPDD 195
            .|:.:...:..|||||||:|||.....|.:.|.:...|...|:..:..:|..|...|||.||...
  Fly   131 TLAPHQCAIWPLLEVLKVLPEEIDSRYLRLGANRREEVHKQLDASAECVLKFLCMCLQREDLDQQ 195

  Fly   196 AL-PKCLAVCASWTKFSMLSPDQVLQRKLFIMAEFILATPLVNG--HLEAAELFVALLEQSLIRK 257
            .: ...|...::|..........|....|..:|..:|:.|..:|  |..|.|...|||.....|:
  Fly   196 RVWNAALRTYSAWLVIHAFPVSHVYNNALTQLAFRLLSLPETSGKLHDNATECVCALLSCINTRQ 260

  Fly   258 E--------LNSCLANSVICLKPAFKRSMGERSLLQ--NYCNIFVNLFQTHFRLTQTNPERLNER 312
            :        ..:.|..:|..|:..:..|:......:  |||.||.:|....|.....:.::.:..
  Fly   261 DGASDPESSFEAQLFGAVCMLETPYHLSVAHEDTDKTINYCRIFTSLCDAFFYDLLADAQKPHYS 325

  Fly   313 LVTIELLLLVAEESPLEVIEASLGMWSSISEEVYLHDDPEMYSVYQPYFVRLLDLLLPRAALPAN 377
            |..::|:||.......||.|.:..:|..:||:::..::.::..:::|:..||:..|...:.:.::
  Fly   326 LKGLDLVLLCVGHFDYEVAEITFHLWYKLSEDLFQRNEDKLTVLFRPHIERLISALFRHSQMESD 390

  Fly   378 YEFMMPPGSADMQRFRELIGEVLLDMAHMIDDDT-VEKLCSIVVDEQSPWMEVEASVFFLRHLIG 441
            ::.::...: :...||..:.:::.|:|.::.... .:::..|:...::.|...||::|.::::..
  Fly   391 HDGLIEENN-NFFDFRRKVSDLIKDVAFIVGSGACFKQMFHILQAPETTWESTEAALFIMQNVAK 454

  Fly   442 NFKEHQTDIISCILKTFFQKDCQQPFIRLQVLELISIPEIV--------SVETIWDCLVNELRRA 498
            |....:.::|..:::...... :|..|.::...::.|.|:.        |:|.:.:.|:..|::.
  Fly   455 NILPDENEVIPKVVEAILNMS-EQTHIAVRYTAILLIGELCDWIENHPESLEAVLNFLLYALQQK 518

  Fly   499 DPMLSAI---------DCRLNLLMPHWNYLVTLAIMVDEFCLKESERCELLCSICTLIRELPAAC 554
            :.:..|.         .||..::. |.:.||.:|..:|.|.:.......||..|..::..||...
  Fly   519 NGLAPAAAIALTSICSACRQKMVC-HISGLVEIARSLDSFQINNDVAIGLLKGISLILTRLPREQ 582

  Fly   555 VQEAKTSILNIR 566
            :|.|...|:..:
  Fly   583 LQPALREIVGFQ 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10950	NP_611200.2	IBN_N	25..91	CDD:197981	27/65 (42%)
		Xpo1	103..>207	CDD:285575	29/104 (28%)
Tnpo-SR	NP_001259961.1	IBN_N	28..94	CDD:281761	28/67 (42%)
		Xpo1	100..248	CDD:285575	40/148 (27%)
		HEAT repeat	427..454	CDD:293787	5/26 (19%)
		HEAT repeat	462..496	CDD:293787	5/34 (15%)
		HEAT repeat	506..531	CDD:293787	3/24 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441201
Domainoid	1	1.000	45	1.000	Domainoid score	I3093
eggNOG	1	0.900	-	-		E1_KOG2081
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12363
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840