DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17287 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_611197.1	Gene:	CG17287 / 36939	FlyBaseID:	FBgn0034202	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	376	Identity:	96/376 - (25%)
Similarity:	140/376 - (37%)	Gaps:	140/376 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 WLPALIILGFLVWSYHVFVYQICIKKVSDYLTIGLLLFFYHL----------LLF----MFLWTW 68
            |.| :|.||         |..||    |....|..:|:::.|          :|.    |.|:.:
Mouse    22 WGP-IIALG---------VIAIC----STMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNY 72

  Fly    69 FRCIFVAPVRIPDQWKISPEDVDKLKRNDGIEGASRVLNYAARNLPIATCTIDGLVRYCKTCWII 133
            |..:|..|..:|..||  ||     |..|.:                       .::|||.|...
Mouse    73 FNAMFAGPGFVPRGWK--PE-----KSQDSM-----------------------YLQYCKVCQAY 107

  Fly   134 KPDRAHHCRTCHMCVLKMDHHCPWIVNCVHFHNFKYFILFLFYAEVYCFYLFCVMVYDLYLICGF 198
            |..|:||||.|:.||:|||||||||.||....|...|.|||..|.:.|.:...:.|..:|
Mouse   108 KAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMY----- 167

  Fly   199 EVTALKNQHS--WNILQY----------------LVCILFNIFTV-----------IMYTVSLLN 234
              |.|.|:.|  ||.::.                |......:|.:           :::.:.:..
Mouse   168 --TQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKI 230

  Fly   235 VSRNRTTMES-------AYATYFLLGGKNNNGFNLGYFVNFRDLYGDKW------YLWP-FPIFS 285
            :.||:|::||       ....|:.|    :..|...|     |: |.||      :.|. .|
Mouse   231 ILRNKTSIESWIEEKAKDRIQYYQL----DEVFIFPY-----DM-GSKWKNFKQVFTWSGVP--- 282

  Fly   286 SRGDGFSFP---------LAHDRLKEVRTGNQKKDNQPTRTQMYK--ENMN 325
             .|||..:|         |..::||      ||.|.: .|:..||  |:.|
Mouse   283 -EGDGLEWPIREGCDQYSLTIEQLK------QKADKR-VRSVRYKVIEDYN 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17287	NP_611197.1	zf-DHHC	125..243	CDD:279823	44/146 (30%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	45/175 (26%)
		SH3_2	317..396	CDD:369452	4/9 (44%)
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820