DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17287 and ZDHHC8

DIOPT Version :9

Sequence 1:	NP_611197.1	Gene:	CG17287 / 36939	FlyBaseID:	FBgn0034202	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001171953.1	Gene:	ZDHHC8 / 29801	HGNCID:	18474	Length:	778	Species:	Homo sapiens

Alignment Length:	271	Identity:	69/271 - (25%)
Similarity:	109/271 - (40%)	Gaps:	54/271 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PIGEGHRRVPCCAVRWLPALIILGFLVWSYHVFVYQIC---IKKVSDYLTIGLLLFFYHLLLFMF 64
            |...|.|..|   .:::|.......||.|..:|....|   .:.||..:.:      |:.::|:|
Human     2 PRSPGTRLKP---AKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAVPV------YNGIIFLF 57

  Fly    65 LWTWFRCIFVAPVRIPDQWKISPEDVDK-------LKRNDGIEGASRVLNYAARNLPIATCTIDG 122
            :...|.   :|....|..:..:.||.||       |.:|..:.|                  |..
Human    58 VLANFS---MATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRG------------------IQV 101

  Fly   123 LVRYCKTCWIIKPDRAHHCRTCHMCVLKMDHHCPWIVNCVHFHNFKYFILFLFYAEVYCFYLFCV 187
            .:::|.||...:|.|..||..|..||...||||||:.||:...|::||.|||.....   ::..|
Human   102 RMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSA---HMVGV 163

  Fly   188 MVYDLYLICGFEVTALKNQHSWNILQYLVCI--LFNIFTVIMYTVSLLNVSRNRTTMESAYATYF 250
            :.:.|..:.. ....|...|: .|...::|:  ||.|..:.:....::.|:|.|||.|.
Human   164 VAFGLVYVLN-HAEGLGAAHT-TITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQ------ 220

  Fly   251 LLGGKNNNGFN 261
             :.||...|.|
Human   221 -VTGKFRGGVN 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17287	NP_611197.1	zf-DHHC	125..243	CDD:279823	38/119 (32%)
ZDHHC8	NP_001171953.1	DHHC	99..224	CDD:366691	40/136 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..352
		PHA03247	<333..771	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	509..540
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810