DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17287 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_611197.1	Gene:	CG17287 / 36939	FlyBaseID:	FBgn0034202	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	65/257 - (25%)
Similarity:	98/257 - (38%)	Gaps:	86/257 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VPCCAVRWLP----ALIIL---GFLVWSYHVFVYQICIKKVSDYLTIGLLLFFYHLLLFMFLWTW 68
            :|...:.|:.    ||:|.   |.:.||..:||..|.:...|          ||.:|:.
Worm   331 LPVTYIFWMGIAEFALLIFNSNGLVHWSVLIFVCSIWVISAS----------FYWILIL------ 379

  Fly    69 FRCIFVAPVRIPDQWKISPEDVDKLKRNDGIEGASRVLNYAARNLPIATCTIDGLV--------- 124
                                      .|.|:             ||.:|......:
Worm   380 --------------------------TNPGV-------------LPRSTTPFKDFIKDLEEKQID 405

  Fly   125 RYCKTCWIIKPDRAHHCRTCHMCVLKMDHHCPWIVNCVHFHNFKYFILFLFYAEVYCFYLFCVMV 189
            |||.||||.|...:|||..|..||...|||||||..||:..|.:.|:.|..  .::.|::|.|::
Worm   406 RYCFTCWIPKTSSSHHCSQCDKCVDGFDHHCPWIHKCVYRKNLRAFVFFCL--TIFMFHVFYVLL 468

  Fly   190 YDLYLI------CGFEVTALKNQHSWNILQYLVCI--LFNIFTVIMYTVSLLNVSRNRTTME 243
            . ||:|      .|||.|.  |.|...::..::.|  :|....:.....|  .:||:.:|:|
Worm   469 L-LYMIGASMNASGFEQTL--NDHGLMVISLILAIPHVFGAGAITCTQFS--QISRHVSTIE 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17287	NP_611197.1	zf-DHHC	125..243	CDD:279823	44/125 (35%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	45/128 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810