DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17287 and dhhc-14

DIOPT Version :9

Sequence 1:	NP_611197.1	Gene:	CG17287 / 36939	FlyBaseID:	FBgn0034202	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001024514.2	Gene:	dhhc-14 / 181109	WormBaseID:	WBGene00044071	Length:	565	Species:	Caenorhabditis elegans

Alignment Length:	292	Identity:	62/292 - (21%)
Similarity:	105/292 - (35%)	Gaps:	82/292 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EGHRRVPCCAVRWLPAL------------IILGFLVWSYHVFVYQICIKKVSDYLTIGLLLFFYH 58
            :|..|..|....::|.:            ..:.:|::.|...:.......:|....:.|:.|.||
Worm   251 QGVSRTSCFRRSFVPPISTYFFFLVPMFGFFMTYLLFKYLPLIIATFSTLISCIFLMVLIRFDYH 315

  Fly    59 ---------------LLLFMFLWT---------WFRCIFVAPV--------RIPDQWKISPEDVD 91
                           .:|.:..|:         |.:.:||..|        ||   ..:.|
Worm   316 DPTYKLLPYGVTIAEAILMVLSWSAYAHWYVPWWAQMLFVLSVLALAFTLFRI---GTLDP---- 373

  Fly    92 KLKRNDGIEGASRVLNYAARN-----LPIATCTIDGLVRYCKTCWIIKPDRAHHCRTCHMCVLKM 151
                     |..|    ||:|     :..|...|....:||.||:|.|.|...||..|..||...
Worm   374 ---------GVVR----AAKNCHQLFVNEAEAGIQHQQKYCFTCFIRKMDHTKHCAVCGFCVNNF 425

  Fly   152 DHHCPWIVNCVHFHNFKYFILFLFYAEV----YCFYLFCVMVYDLYLICGFEVTALK---NQHSW 209
            ||||||:.:||...|.:.||:|:....|    ||      |....|.:...|...|:   ...::
Worm   426 DHHCPWLNSCVTRRNMREFIMFVISVSVSSAIYC------MATSHYALLQIEDHGLEEFLETDAF 484

  Fly   210 NILQYLVCILFNIFTVIMYTVSLLNVSRNRTT 241
            .::..::..:..:...:::.|.:..:|:..||
Worm   485 LMITIILSAMHALMLAVLFCVQMNQISQGVTT 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17287	NP_611197.1	zf-DHHC	125..243	CDD:279823	35/124 (28%)
dhhc-14	NP_001024514.2	ANK	19..143	CDD:238125
		Ank_2	30..120	CDD:289560
		ANK repeat	55..87	CDD:293786
		ANK repeat	89..120	CDD:293786
		Ank_2	94..222	CDD:289560
		ANK	117..244	CDD:238125
		ANK repeat	190..222	CDD:293786
		PulO	<261..>367	CDD:224900	14/105 (13%)
		zf-DHHC	394..521	CDD:279823	36/129 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910