DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17287 and ZDHHC19

DIOPT Version :9

Sequence 1:	NP_611197.1	Gene:	CG17287 / 36939	FlyBaseID:	FBgn0034202	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001034706.1	Gene:	ZDHHC19 / 131540	HGNCID:	20713	Length:	309	Species:	Homo sapiens

Alignment Length:	272	Identity:	59/272 - (21%)
Similarity:	93/272 - (34%)	Gaps:	103/272 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LLLFFYHLLLFMFLWTW----------------FRCIFVAPVRIPDQWKISPEDVDKLKRNDGIE 100
            :||.|:..|.|.|...|                |...|.:.|      .::..|...|.:....:
Human    36 VLLVFFSGLFFAFPCRWLAQNGEWAFPVITGSLFVLTFFSLV------SLNFSDPGILHQGSAEQ 94

  Fly   101 GASRV----LNYAARNLPIATCTIDGLVRYCKTCWIIKPDRAHHCRTCHMCVLKMDHHCPWIVNC 161
            |...|    :|:.|..|           ::|..|...:|.|.:||..|::||...||||.|:.||
Human    95 GPLTVHVVWVNHGAFRL-----------QWCPKCCFHRPPRTYHCPWCNICVEDFDHHCKWVNNC 148

  Fly   162 VHFHNFKYFILFLFYAEVYCFYLFCVMVYDLYLICGFEVTALKNQHSWNILQYLVCILFNIFTV- 225
            :...||::|:|.:.   ..|.|...::|                          .|::|.:.|.
Human   149 IGHRNFRFFMLLVL---SLCLYSGAMLV--------------------------TCLIFLVRTTH 184

  Fly   226 -------------------IMYTVSLLNVSRNRTTMESAYATYFLLGGK-----NNNGFNLGYFV 266
                               ::..:|||.:.: ..::.||..||   .||     ..|.|:.|...
Human   185 LPFSTDKAIAIVVAVSAAGLLVPLSLLLLIQ-ALSVSSADRTY---KGKCRHLQGYNPFDQGCAS 245

  Fly   267 NFRDLYGDKWYL 278
            |        |||
Human   246 N--------WYL 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17287	NP_611197.1	zf-DHHC	125..243	CDD:279823	29/137 (21%)
ZDHHC19	NP_001034706.1	DHHC	109..>181	CDD:366691	26/111 (23%)
ZDHHC19	NP_001034706.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..309
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810