DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cda9 and ChLD3

DIOPT Version :9

Sequence 1:	NP_001286519.1	Gene:	Cda9 / 36934	FlyBaseID:	FBgn0034197	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_609806.1	Gene:	ChLD3 / 35002	FlyBaseID:	FBgn0032598	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	140/385 - (36%)
Similarity:	196/385 - (50%)	Gaps:	49/385 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 AEPCKPSKCKLPDCRCS------DAALPTSKFQGKENQIPQFVTITFDDAVNAVNFAQYELLFDG 97
            |..|.|.||.||.|.||      ..:||.       ..:||.:.:|||||:|..|:.    ||..
  Fly   211 AGACDPRKCHLPQCFCSKDGTQIPGSLPA-------QSVPQMILLTFDDAINHDNWE----LFSK 264

  Fly    98 LI------NPDGCGAAGTFFLSHEYTDYVRVNALYRAGHEIALHSVTHGDGTDYWRSADVPTIE- 155
            ::      ||:||...|||::||.:|:|..|..|:..|||||:||||| .|.:.|.|.:. |||
  Fly   265 VLFTQHRRNPNGCPIKGTFYVSHPFTNYQYVQKLWNDGHEIAVHSVTH-RGPEMWWSKNA-TIED 327

  Fly   156 --REFGAQLKMLETFAKVNPKKIQGMRLPFLQISGNNTFEAARRLGLTYDSSWPTQKFKDPAMWP 218
              .|...|..::..||.|..::|:|||:|||::..|..|...:..|..||||. .....:|.:||
  Fly   328 WFDEMVGQANIINKFAAVRMEEIRGMRVPFLRVGWNRQFLMMKEFGFVYDSSM-VAPHSNPPLWP 391

  Fly   219 YTLDYKSKQDCQIG---PCPEASIPGFWVNPMVTWTDTEGYSCSMIDACVYPPEDDMDELFDWMM 280
            ||||||....| .|   .||..|.||.| ..::...:...|.|.|:|.|  ||....::::..:.
  Fly   392 YTLDYKMPHSC-TGVNQNCPSRSYPGIW-ELVMNQLEVGEYMCGMVDTC--PPHLSGEDVYRMLT 452

  Fly   281 ENFNRHYLGNRAPFGMYLHAAWFSRGRNYFGAFKKFINHLNTYSDVYFTGISRMLEYVRKPTLGS 345
            .||.||||.||||||:|.|:.||.: .:|..||.||::.|....||:|....:.::::|.||..:
  Fly   453 HNFKRHYLSNRAPFGLYFHSTWFKK-VDYLNAFLKFLDDLQKLPDVFFVTNQQAIQWMRHPTPSN 516

  Fly   346 PF----------KDCPDLPEAECRAVQ-CHVQKMSTGEERYMTVCDKCPSVYPWLDNPLG 394
            ..          ||. |..|..|.... |.|:.....|:|:...|.:||:.|||:.|..|
  Fly   517 QLHQFESWHCQPKDL-DPHEQVCNTPNVCKVRSRVLQEDRFFYTCMECPAQYPWIRNEFG 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cda9	NP_001286519.1	CE4_CDA_like_2	72..341	CDD:200597	109/280 (39%)
ChLD3	NP_609806.1	CBM_14	<111..149	CDD:279884
		LDLa	168..202	CDD:238060
		CE4_CDA_like_1	243..512	CDD:200596	109/280 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060206at2759
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020