DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15605 and RWDD1

DIOPT Version :9

Sequence 1:	NP_611191.1	Gene:	CG15605 / 36933	FlyBaseID:	FBgn0034196	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_057036.2	Gene:	RWDD1 / 51389	HGNCID:	20993	Length:	243	Species:	Homo sapiens

Alignment Length:	131	Identity:	36/131 - (27%)
Similarity:	58/131 - (44%)	Gaps:	20/131 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 QENEVRTMHYL-GLAYVVLSRRPNLQLKVPLSTQNYEDGAIVGAGERGGYALQLLFTCAANYPLA 95
            |.||:..:..: ..::.|||..|. ...:.::::..|:...|        ...|.||.:..||..
Human     8 QRNELEALESIYPDSFTVLSENPP-SFTITVTSEAGENDETV--------QTTLKFTYSEKYPDE 63

  Fly    96 RPLVEIVEKRNVSDAFEQVLRKEIDLILEEHLGLQMIVPVVTRLQITLN----------TEMKRQ 150
            .||.||..:.|:.|.....:.|.:.|..||:||:.||..:||.:|..||          .|.|:|
Human    64 APLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQ 128

  Fly   151 R 151
            :
Human   129 K 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15605	NP_611191.1	RWD	33..145	CDD:214735	32/122 (26%)
RWDD1	NP_057036.2	RWD	6..111	CDD:368608	31/111 (28%)
		Interaction with DRG2. /evidence=ECO:0000250	142..197
		DFRP_C	<144..217	CDD:374615
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..243
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003763
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810