DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Amy-d and CD98hc

DIOPT Version :9

Sequence 1:	NP_523768.1	Gene:	Amy-d / 36932	FlyBaseID:	FBgn0000078	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001262354.2	Gene:	CD98hc / 40941	FlyBaseID:	FBgn0037533	Length:	629	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	95/509 - (18%)
Similarity:	152/509 - (29%)	Gaps:	197/509 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSSK 137
            ||::|            |...:||| |:.|....|:     |...:.:.|..|      ..|::.
  Fly   180 PWYKR------------GPHAKFAS-VETCRPEDVQ-----VAKKLVSAGAIY------ELPAAL 220

  Fly   138 SY----PGVP---------YSS------LDFNPTCAISN---YND--ANEVRNCELV-------- 170
            :|    |.|.         |..      ||..|..|..|   ..|  ||..:....|
  Fly   221 TYDVKKPEVEEKIKHLVALYQGSDTRVILDLTPNYAAKNSQLVQDAIANPEKRSAFVWVSGGKAL 285

  Fly   171 ----------------------------GLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAK 207
                                        |..||...::.::::....|.||:.|||.|||:...|
  Fly   286 PNNWLKVGGNRSAWEKVGDNYVLSQFEDGYYDLKMNSTIIRNEFGAVLKHLVALGVRGFRLKNTK 350

  Fly   208 HMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGK 272
            ..      .::..|:    |...:|..|.:           ::..:|| |..:..:......:|.
  Fly   351 FF------ALFDSLE----DEQISSSPKDF-----------SLGPNEY-GFYSHRQTTFLSGLGD 393

  Fly   273 VFRGKDQLQYLTNWGTAWGFAASDRSLVFVDN-------HDNQRGHGAGGAD---------VLTY 321
            |.  .|.|..:.|        |||.:...|..       :......||.|.|         ||:.
  Fly   394 VL--YDYLSIVKN--------ASDEAFFSVAEDVMEPQVYQLSGDSGAYGIDLPMYGNFVKVLSK 448

  Fly   322 KVPK--------------------QYKMASAFMLAHPFGTPRVMSSFS-FTDTDQGPPTTDGHNI 365
            ..|.                    |:.:|..::     .||:..|:.: |.....|.|.     :
  Fly   449 SKPDTSLQKELDNTLAQSGTDSWLQWNLADVYV-----DTPQDPSALAMFLSLLPGVPV-----V 503

  Fly   366 ASPIFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGLDEIQNWWDSGSN------QISFSR---GS 421
            |.......|      |.|..:|||         ..|.:..::.....|      .::|||   |:
  Fly   504 AVDAVAYQN------VTEETYRQI---------TSLRKTASYMHGNLNLYQADPLVAFSRIKSGN 553

  Fly   422 RG-FVAFN------NDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVTVG 468
            .| ||.||      ..|:.:..:|...:....:.:..:.:...|   ||....|
  Fly   554 PGYFVIFNPTELPQASNFTIPDNLPDKMTVSYFSEQYNNNMDNS---GKVAHAG 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amy-d	NP_523768.1	AmyAc_bac_euk_AmyA	28..399	CDD:200456	78/422 (18%)
		Alpha-amylase	54..342	CDD:278554	65/364 (18%)
		Aamy_C	405..493	CDD:214749	16/80 (20%)
CD98hc	NP_001262354.2	AmyAc_maltase-like	117..593	CDD:200468	91/493 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43447
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000