Protein Alignment Spn53F and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 103/422 - (24%)
• Similarity: 173/422 - (40%)
• Gaps: 67/422 - (15%)

  Fly    19 NSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSE----- 78
            |::...:|:..|.....::||.||...:.:::..:.:|...|.:.||.:.:|:.....:|
Human    20 NTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPD 84

  Fly    79 --YKPKTQKIFAMS----VKKA--PV---------AKSLTRFYVRQNM----KMSTEYRVFMRHT 122
              .|...||:.|.|    .||.  |:         ...|...|..|.:    ::.|:|.:.:.:.
Human    85 PCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANR 149

  Fly   123 EGRARNIAFAREQLDEVNTFYSHEMGEQIG-QVVKES-------WWKPNSQG------------- 166
            ....:.....:|.||.|..|| |...|.:. |...|.       |.:..|||
Human   150 LYGEQEFPICQEYLDGVIQFY-HTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINA 213

  Fly   167 ----LLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVP 227
                :||||::|...||..|:.|.|....|.:||.::..:.||.:...:..|.:..:||..:.:.
Human   214 ETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMR 278

  Fly   228 FSHGDLRMLLIKP----DQPDGLAALQMKL--QAMNILSVARNLTMMDVFVGIPKFKIHSDLELS 286
            ::.|.|.|.::.|    |...||..|:.|:  :.|...|.:.|::...|.:..|:|.:....:|:
Human   279 YTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLN 343

  Fly   287 PAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTD---VGNGSLTHTF 348
            ...:.|||.|||..:::..|.:..:.|..:..:||....|..|.|....:..   |...||....
Human   344 SILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLRSWV 408

  Fly   349 NGVKYFLATHPFAFYIIDN--TSIYFAGHVTS 378
            .    |.|.|||.|:|..|  .:|.|.|.|.|
Human   409 E----FNANHPFLFFIRHNKTQTILFYGRVCS 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	100/412 (24%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	103/422 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830