DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpine3

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	76/389 - (19%)
Similarity:	140/389 - (35%)	Gaps:	61/389 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQKIFAMS 90
            ||.:.....:..|.:.|...:..|:..:......:...|:.:|:.|                  :
  Rat    39 LYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEALGY------------------T 85

  Fly    91 VKKAPVAKSLTRFYV-----RQNMKMSTEYRVFMR----------HTEGRARNIAFAREQLDEVN 140
            |:...|.:.|...|:     .|.:.|.....:||:          ....|..|.:.......|.|
  Rat    86 VQDPRVREFLHTVYITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVSRWANSSLELADFSEPN 150

  Fly   141 TFYSH--------EMGEQIGQVVKESWWKP---NSQGLLVNAIFFNLSWERTFNPEATYPREFRV 194
            |....        ..||..|..:   |.:.   ::|..:|:.:.|..||::.|:..|..|..|..
  Rat   151 TTTMEASKGTTRPSTGEGPGSPL---WGRAGALSTQLSIVSTMTFQSSWQQRFSSVALQPLPFTC 212

  Fly   195 NATKSVMIPMMHEDSKFAFG----ILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQA 255
            .....:.:|.||:.::.::|    ..|:......|:........:|::..|:...|..::..|.|
  Rat   213 AHGLVLQVPAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQDKGTPLDHIEPHLTA 277

  Fly   256 --MNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDG 318
              :::.:.......||||  :|:|:|.:..:|.......||.|:|.|.|:....:.....|.:..
  Rat   278 RVIHLWTTRLKRARMDVF--LPRFRIQNQFDLKSILRSWGITDLFDPLKANLKGISGRDGFYVSE 340

  Fly   319 VIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIIDNTSIYFA---GHVTSF 379
            |.|....|..|:  ||.|. .....|....:....|.|..||.|.:.::.::...   |.|.:|
  Rat   341 VTHKAKMELSEE--GTKSC-AATAVLLLRRSRTPAFKADRPFIFLLREHNTVAVRITHGKVANF 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	74/384 (19%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	75/386 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110