Protein Alignment Spn53F and Serpina12

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 401
• Identity: 84/401 - (20%)
• Similarity: 158/401 - (39%)
• Gaps: 73/401 - (18%)

  Fly    12 SRYRAQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRK--------- 67
            :|..|:.|.:...:|...:.::....||..|...|.::...:.:|.:....|:||:
Mouse    45 ARQLARHNMEFGFKLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSN 109

  Fly    68 -----AMHYRGTHLSEYKPKTQ----KIFAMSVKKAP------VAKS-------LTRFYVRQNMK 110
                 |.||....|::....|:    ....|..|..|      :||:       ||.|...:|.:
Mouse   110 WDVHAAFHYLLHKLNQETEDTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQ 174

  Fly   111 MSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFN 175
                                      .::|.:.|.:...:|..:||..  .|.:..:|.|.|:|.
Mouse   175 --------------------------KDINRYISQKTHSRIKNMVKSI--DPGTVMILTNYIYFR 211

  Fly   176 LSWERTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKP 240
            ..|:..|:|:.|...||.:...|:|.:|||.:...:.......|..|.:.:|: .|::....:.|
Mouse   212 GRWQYEFDPKQTKEEEFFIEKGKTVKVPMMFQRGLYDMAYDSQLSCTILEIPY-RGNITATFVLP 275

  Fly   241 DQPDGLAALQMKLQAMNILSVARNL---TMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSK 302
            |. ..|..|:..||| :|.:..::|   .::||:|  ||.:|.|...:.....::||..||:.:.
Mouse   276 DN-GKLKLLEQGLQA-DIFAKWKSLLSKRVVDVWV--PKLRISSTYNMKKVLSRLGISKIFEENG 336

  Fly   303 SFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIIDN 367
            .. |.:..:.:.::...:|....:..|:|:   ....|:|:.|......::.....||...|.:|
Mouse   337 DL-TRISSHRSLKVGEAVHKAELKMDEKGM---EGAAGSGAQTLPMETPRHMKLDRPFLMMIYEN 397

  Fly   368 --TSIYFAGHV 376
              .|:.|...:
Mouse   398 FMPSMVFLARI 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	81/386 (21%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	82/393 (21%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010