Protein Alignment Spn53F and SERPINE3

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 82/373 - (21%)
• Similarity: 144/373 - (38%)
• Gaps: 45/373 - (12%)

  Fly    26 LYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQKIFAMS 90
            ||.::....:..|.:.|...:...:..:..|.|....:|:..|:.|. .|....|.....::|
Human    37 LYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYT-VHDKRVKDFLHAVYA-- 98

  Fly    91 VKKAPVAKSLTR------FYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVN-TFYSHEMG 148
              ..|.:...|.      .:|:....:|.   .|:.|....| |.:.....|.|.| |......|
Human    99 --TLPTSSQGTEMELACSLFVQVGTPLSP---CFVEHVSWWA-NSSLEPADLSEPNSTAIQTSEG 157

  Fly   149 ---EQIGQVVKE---SW-WKPNS----QGLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMI 202
               |..|....|   .| |:..|    |.:||:.:.|..:|.:.|:...|....|.......:.:
Human   158 ASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQV 222

  Fly   203 PMMHEDSKFAFGILGNLKATA-----VL-VPFSHGDLRMLLIKP-DQPDGLAALQMKLQA--MNI 258
            ||||:.::..:   |..:.||     || :|:....:.:.|:.| |:...|:.::..|.|  :::
Human   223 PMMHQTTEVNY---GQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHL 284

  Fly   259 LSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVV 323
            .:.:.....||||  :|:|:|.:...|.......|:.|:|.|.|:....:.....|.:...||..
Human   285 WTTSLRRARMDVF--LPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGISGQDGFYVSEAIHKA 347

  Fly   324 TFEFQEQGIGTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIID-NTSI 370
            ..|..|:|   .........|....:.:..|.|..||.:::.: ||.|
Human   348 KIEVLEEG---TKASGATALLLLKRSRIPIFKADRPFIYFLREPNTGI 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	82/373 (22%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	82/373 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		8/30 (27%)