Protein Alignment Spn53F and SERPINB4

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 99/407 - (24%)
• Similarity: 169/407 - (41%)
• Gaps: 66/407 - (16%)

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHY-RGTHLSEY 79
            ::.|::...:|:.....|..| ||.:|...|.|::..:.:|.:::.::||.|.:|: :.|..:..
Human     5 SEANTKFMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTE 68

  Fly    80 KPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYS 144
            |..|..:...........|.||.|     .|.:..|.:.:.:.....:...|.:|.||.:..||.
Human    69 KAATYHVDRSGNVHHQFQKLLTEF-----NKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQ 128

  Fly   145 HEM-GEQIGQVVKESWWKPNS---------------QG--------LLVNAIFFNLSWERTFNPE 185
            ..: ........:||..|.||               .|        :|||||:|...||..|..|
Human   129 TSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKE 193

  Fly   186 ATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQ 250
            .|...:|..|......:.||.:.:.|.|.:|.:::|..:.:|:...||.|:::.|::.|||..|:
Human   194 NTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLE 258

  Fly   251 MKLQAMNIL--SVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFS--TLLHRN 311
            .||.|..::  :..:|:....|.:.:|:||:....:|......||:.:||......|  |..|
Human   259 EKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSH-- 321

  Fly   312 TNFRIDGVIHVVTFEFQEQGI-------------GTPSTDVGNGSLTHTFNGVKYFLATHPFAFY 363
             ...:..|:|....|..|:|:             .:|||:             :.|...|||.|:
Human   322 -GLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTN-------------EEFCCNHPFLFF 372

  Fly   364 IIDN--TSIYFAGHVTS 378
            |..|  .||.|.|..:|
Human   373 IRQNKTNSILFYGRFSS 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	98/403 (24%)
SERPINB4	NP_002965.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	99/407 (24%)