Protein Alignment Spn53F and Serpinb2

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_067728.1
• Gene: Serpinb2 / 60325
• RGDID: 621823
• Length: 416
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 105/419 - (25%)
• Similarity: 181/419 - (43%)
• Gaps: 70/419 - (16%)

  Fly    19 NSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKT 83
            |:.....|...|..|.|.:||..|...|.|::..:::|.:.:..||:.|.:::......:..|..
  Rat     8 NTMFALNLLKQIEQSNSTQNIFISPWSISSTLAIVFLGAQANTEEQMAKVLNFDKIGSYDLTPGN 72

  Fly    84 QK-----IFAMSVKK--APVA-------------------------------KSLTRFYVRQNMK 110
            .:     .||..:::  .|||                               :|..:.:..::.:
  Rat    73 PENFHGCDFAQHIQRDNYPVAILQAQARDKIHSAFSSLSSTINTPRLGDYLLESANKLFGEKSAR 137

  Fly   111 MSTEYRVFMR-----HTEGRARN-IAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLV 169
            ...||  ..|     .||..|.: :..|.|...::|::...:...:|..::.|.....:::.:||
  Rat   138 FKEEY--IQRCKKYYSTEPEAVDFLECANEARKKINSWVKTQTKGEIPNLLPEGSVDEDTKMVLV 200

  Fly   170 NAIFFNLSWERTFNP--EATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGD 232
            |.|:|...|:..|..  ...||  ||||..:|..:.||:...|...|.:.:||...:.:|:. |:
  Rat   201 NTIYFKGRWKTPFQKRLNGLYP--FRVNLNESKPVQMMYLREKLNIGYIKDLKTQILELPYI-GN 262

  Fly   233 LRMLLIKPDQ-PDGLAALQMKLQAMNILSVAR-----NLTMMDVFVGIPKFKIHSDLELSPAFEK 291
            :.|.|:.||: .|....|:|..:.:|..:..:     .|...||.|.|||||:..:.||.|..::
  Rat   263 ISMFLLLPDEIEDSSTGLEMLEREINFDNFNKWISKETLDEDDVLVYIPKFKLAQNYELKPILQR 327

  Fly   292 MGIKDIFKPSKS-FSTLLHRNTNFRIDGVIHVVTFEFQEQGI----GTPSTDVGNGSLTHTFNGV 351
            ||::|.|...|: ||.:...|..| :..|.|..|.:..|:|.    ||.:...|     .|.:|.
  Rat   328 MGMEDAFNKGKADFSGMSESNDLF-LSEVFHQATVDVNEEGTVAAGGTGAVMTG-----RTGHGG 386

  Fly   352 KYFLATHPFAFYIIDN--TSIYFAGHVTS 378
            ..|:|.|||.|:|::|  .:|.|.|..:|
  Rat   387 PQFVADHPFLFFIMNNITRTILFVGRFSS 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	104/418 (25%)
Serpinb2	NP_067728.1	serpinB2_PAI-2	2..416	CDD:381029	105/419 (25%)