DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	375	Identity:	77/375 - (20%)
Similarity:	150/375 - (40%)	Gaps:	24/375 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NSQLPDELYAAIVNS--FSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKP 81
            |:.....||..::.|  :.::||.||...:..::..:.:|...|..:|:...:.|..|..|  ..
Zfish    40 NNDFAFHLYKRVIESPDYQSKNIFFSPFSVSIALSELSLGAGGDTKQQLLSGIGYNSTTFS--TE 102

  Fly    82 KTQKIFAMSVKKAPVAKSL-----TRFYVRQNMKMSTEYRVFMR---HTEGRARNIAFAREQLDE 138
            :..::|...::.......:     |..|.....|..:::...|:   |::|...:.. .:|.:|:
Zfish   103 EMHQLFHSLLEDIGNRTGVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDGFTVDFR-VKETVDQ 166

  Fly   139 VNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIP 203
            :|.:...:...:..|.|.:  .:.::...|:..|:|...|::.|.||.|....|.::...:|.:.
Zfish   167 INNYAKKKTQGKFNQAVDD--LEEDTLMFLLTYIYFKGKWDKPFKPEKTRESTFHIDDKTTVPVQ 229

  Fly   204 MMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPD---QPDGLAALQMKLQAMNILSVARNL 265
            |||:..:........| :|.||.........|.|..||   :...:..|:|.:...:.....|:.
Zfish   230 MMHQYERLKVFYDAEL-STKVLCLDYKDSFSMFLAVPDDKMEHKNIKDLEMTVSRQHFEKWRRSA 293

  Fly   266 TMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQ 330
            ....|.:.:||..:.:...|....:.||:.|:|....:|:.:  ......:..|:|..|.:..||
Zfish   294 FKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKANFTGV--SEEKIFVSKVLHKATLDIDEQ 356

  Fly   331 GIGTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIID--NTSIYFAGHVTS 378
            |. |.:...|........|.:.......||..:|.|  |.:|.|.|.|.:
Zfish   357 GT-TAAAVTGVSMRVRLHNPLSILKFNRPFMVFITDQTNDNILFFGKVVN 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	75/365 (21%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	76/371 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110