DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and serpini1

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001122164.1	Gene:	serpini1 / 557627	ZFINID:	ZDB-GENE-060503-390	Length:	415	Species:	Danio rerio

Alignment Length:	406	Identity:	92/406 - (22%)
Similarity:	182/406 - (44%)	Gaps:	38/406 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VLLLILLG---ISRYRAQKNSQLPDE--------LYAAIVNSFSNRNIMFSTEMIRSSMLFIYVG 56
            :|||::|.   :.|....:.|.:|::        ||..:..|....||:||...:..::..:.:|
Zfish     1 MLLLVVLPPLLLLRGCFCQASDVPEDVTAEFSVRLYHQLQISSGEENIIFSPLSVALALGMVELG 65

  Fly    57 VEEDESEQIRKAMHYRGTHL---SEYKPKTQKIFAMSV-KKAPVAKSLTRFYVRQNMKMSTEY-R 116
            ......::||:|:.|  :|.   .|:........|:|. ::..|.:.....:::..:..:.:: :
Zfish    66 ARGSSLQEIRQAVGY--SHFREDEEFSLLRNLSQALSTDEEQYVVRLANSLFLQSGVHFNEDFLQ 128

  Fly   117 VFMRHTEGRARNIAFAREQ--LDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWE 179
            :..::.......:.|::..  .:.:|::..:....:|..:|....:..::..:||||::|..||:
Zfish   129 LMKKYFRAEVETVDFSQSTAVAERINSWVLNHTESKIQNLVSAEDFSSSTMIMLVNAVYFRGSWK 193

  Fly   180 RTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGIL--GNLKATAVL----VPFSHGDLRMLLI 238
            ..|.||.|....|..:....|...||::...|.:|..  |..:|..|.    :.:...|:.|:::
Zfish   194 NQFRPENTRTFSFTRDDGSEVQTLMMYQQGDFYYGEFSDGTTEAGGVYQVLEMLYEGEDMSMMIV 258

  Fly   239 KPDQPDGLAALQMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKS 303
            .|.|...||:|:..::|..:...|.|:....|.|.:|:||:...::|..:.:::||:.||.....
Zfish   259 LPRQEVPLASLEPIIKAPLLEEWANNVKRQKVEVYLPRFKVEQKIDLRESLQQLGIRSIFSKDAD 323

  Fly   304 FSTLLHRNTNFR---IDGVIHVVTFEFQEQGIGTPSTDVGNG--SLTHTFNGVKYFLATHPFAFY 363
            .|.:..:.|:.:   |...:.....|..|:|   .....|:|  :||.|.......:|.||| |:
Zfish   324 LSAMTAQMTDGQDLFIGKAVQKAYLEVTEEG---AEGAAGSGMIALTRTLVLYPQVMADHPF-FF 384

  Fly   364 IIDNT---SIYFAGHV 376
            ||.|.   ||.|.|.|
Zfish   385 IIRNRKTGSILFMGRV 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	84/379 (22%)
serpini1	NP_001122164.1	SERPIN	25..414	CDD:294093	85/382 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030