DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinb9h

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001357856.1	Gene:	Serpinb9h / 544923	MGIID:	3709608	Length:	377	Species:	Mus musculus

Alignment Length:	404	Identity:	81/404 - (20%)
Similarity:	167/404 - (41%)	Gaps:	73/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMH-------YRG 73
            :|.|......|...:.....::|:.:|...|.|::..:.:|.:.|.:.||.:|:|       ::|
Mouse     5 SQANGTFAIHLLKVLCQDNPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALHLNPDEDVHQG 69

  Fly    74 THLSEY---KPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYR---VFMRHTEGRARNIA-F 131
            ..|..:   |...|| :.:::        ..|.:|....::...::   :...|:|....:.| .
Mouse    70 FQLLLHNLNKQNNQK-YCLTM--------ANRLFVENTCELLPTFKESCLKFYHSEMEQLSFAEA 125

  Fly   132 AREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNA 196
            |.|....:|.:.|.:...:|..::.:......::.:|.||::|:.:|.:.|....|....|::|.
Mouse   126 AEESRQHINMWVSKQTNGKIPDLLSKDSVNSQTRLILANALYFHGTWCKRFEKNRTKEMPFKINK 190

  Fly   197 TKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSV 261
            .::..:.||..:.......:..::|..:::|:...||..:::.||            :.::|..|
Mouse   191 KETRPVQMMWREDTLFHAYVKEIQAQVLVMPYEGIDLNFVVLLPD------------EGVDISKV 243

  Fly   262 ARNLTM--------------MDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNT 312
            ..|||.              .:..|..|||::..|.:::...:.:||.::|..||:..:.:....
Mouse   244 ENNLTFEKLTAWTKPEFMNRTEFHVYYPKFQLQEDYDMNSLLQHLGILNVFDGSKADLSGMSTKE 308

  Fly   313 NFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVKY-----------FLATHPFAFYIID 366
            |..:...:|....|..|:|     |:....|      .|::           |.|.|||.|:|:.
Mouse   309 NLCLSEFVHKCVVEVNEEG-----TEAAAAS------AVEFIFLCSGPDPETFCADHPFLFFIMH 362

  Fly   367 NT--SIYFAGHVTS 378
            :|  ||.|.|..:|
Mouse   363 STTNSILFCGRFSS 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	78/391 (20%)
Serpinb9h	NP_001357856.1	serpinB	7..374	CDD:381072	79/398 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830