Protein Alignment Spn53F and SERPINB6

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 84/378 - (22%)
• Similarity: 154/378 - (40%)
• Gaps: 59/378 - (15%)

  Fly    35 SNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQKIFAMSVKKAPVAKS 99
            :::|:.||...:..::..:|:|.:.:.:.|:.:.:.                |..|.....:.:.
Human   101 NSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILS----------------FNKSGGGGDIHQG 149

  Fly   100 LTRFYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYSHEMGEQ--IGQVVK-----E 157
            ........| |..|:|.:.|.:.....::..|.....|....||..||.|.  |..|.|     .
Human   150 FQSLLTEVN-KTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHIN 213

  Fly   158 SWWKPNSQG-----------------LLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIPMM 205
            :|....::|                 :||||::|..:|:..|:.|.|..|.|:|:..:...:.||
Human   214 TWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMM 278

  Fly   206 HEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSVARNLTMMD- 269
            .:.|.|....:|.:....:::|:...:|.|:::.||:...|..::.:|.....:...| |.|||
Human   279 FKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTR-LDMMDE 342

  Fly   270 --VFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKS-FSTLLHRNTNFRIDGVIHVVTFEFQEQG 331
              |.|.:|:||:....::......:|:.|.|:..|: ||.:  ..|:..:..|:|....|..|:|
Human   343 EEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM--SQTDLSLSKVVHKSFVEVNEEG 405

  Fly   332 IGTPSTDVGNGS----LTHTFNGVKYFLATHPFAFYI--IDNTSIYFAGHVTS 378
                 |:....:    :......|..|.|.|||.|:|  .....|.|.|..:|
Human   406 -----TEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	84/378 (22%)
SERPINB6	XP_011512974.1	serpinB6_CAP	79..454	CDD:381031	84/378 (22%)