Protein Alignment Spn53F and SERPINB5

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 97/405 - (23%)
• Similarity: 166/405 - (40%)
• Gaps: 83/405 - (20%)

  Fly    19 NSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKT 83
            ||....:|:..:.......|::||...:.:|:....||.:.|.:.:|.:.:|:.
Human     8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFE----------- 61

  Fly    84 QKIFAMSVKKAPVA-----------------KSLTRFYVRQNMKMSTEYRVFMRHTEGRARNIAF 131
                  :||..|..                 |.:.|.||.:::.:|||   |:..|:.     .:
Human    62 ------NVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTE---FISSTKR-----PY 112

  Fly   132 AREQLDEVNTFYSHEMGEQIGQV---VK-------ESWWKPNSQG-----LLVNAIFFNLSWERT 181
            |:| |:.|:  :..::.|..||:   :|       |:....||..     |:|||.:|...|.:.
Human   113 AKE-LETVD--FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKK 174

  Fly   182 FNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKP----DQ 242
            |:...|....||||.|.:..:.||:.::.|..|.:.::....:.:||.:..|.|.::.|    |:
Human   175 FSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDE 239

  Fly   243 PDGLAALQMKLQAMNILSVARNLTMMD--VFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFS 305
            ..||..::.:|.:.::.......||.:  |.:.|||||:...::.....|.:|:|.||....|..
Human   240 STGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDF 304

  Fly   306 TLLHRNTNFRIDGVIHVVTFEFQEQG---IGTPSTDVGNGSLTH--TFNGVKYFLATHPFAFYII 365
            :.:.......:..|||.|..|..|.|   |..|...:    |.|  ..|      |.|||.:.|.
Human   305 SGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARI----LQHKDELN------ADHPFIYIIR 359

  Fly   366 DN--TSIYFAGHVTS 378
            .|  .:|.|.|...|
Human   360 HNKTRNIIFFGKFCS 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	94/395 (24%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	97/405 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930