Protein Alignment Spn53F and SERPINA4

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 86/390 - (22%)
• Similarity: 142/390 - (36%)
• Gaps: 49/390 - (12%)

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYK 80
            |..|:......|..|.:....:||.||...|.::...:.:|.......||.:.:.:..|.|||..
Human    89 APANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 153

  Fly    81 PKTQKIFAMSVKKAPVAKSLTR----FYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNT 141
            ........:.....|.....||    .::..|:|...:   |:..|........|.....|.|.|
Human   154 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAK---FLNDTMAVYEAKLFHTNFYDTVGT 215

  Fly   142 FY---SHEMGEQIGQVVK-ESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMI 202
            ..   .|...|..|::|. .|..|.:...:|||.|:|...||:.|....|.|::|.|:...:|.:
Human   216 IQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRV 280

  Fly   203 PMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQP-----DGLAALQMKLQAMNILSVA 262
            |||.:|.:..:.:.......:||.....||..:..|.|:|.     :.:...:|.::..|:|...
Human   281 PMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKR 345

  Fly   263 RNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTL-----LHRNTNFRIDGVIHV 322
            .....:::.  :|||.|.....|.....::|..|:|......|.:     |..:.:|      |.
Human   346 NFYKKLELH--LPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSF------HK 402

  Fly   323 VTFEFQEQGIGTPSTDVGNGSLTHTFNGVKYFLA---------THPFAFYIIDNT--SIYFAGHV 376
            .|.:..|         .|..:...|...:|:|.|         ..||...|...:  |:.|.|.|
Human   403 ATLDVDE---------AGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKV 458

  Fly   377  376
            Human   459  458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	83/379 (22%)
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	84/386 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020