Protein Alignment Spn53F and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 77/371 - (20%)
• Similarity: 145/371 - (39%)
• Gaps: 35/371 - (9%)

  Fly    26 LYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQ-----K 85
            ||..:.:..::.||.||...|.::...:.:|.:.|..::|.:.:::..|.:    |:.|     :
Human    61 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEI----PEAQIHEGFQ 121

  Fly    86 IFAMSVKKAPVAKSLTR---FYVRQNMKMSTEYRVFMR---HTEGRARNIAFAREQLDEVNTFYS 144
            ....::.:......||.   .::.:.:|:..::...::   |:|....|.....|...::|.:..
Human   122 ELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186

  Fly   145 HEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIPMMHEDS 209
            .....:|..:|||  ...::...|||.|||...|||.|..:.|...:|.|:...:|.:|||....
Human   187 KGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLG 249

  Fly   210 KFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSVARNLTMMDVFVGI 274
            .|.......|.:..:|:.:. |:...:...||: ..|..|:.:|....|.....|.......:.:
Human   250 MFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHL 312

  Fly   275 PKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTDV 339
            ||..|....:|.....::||..:|......|.:. .....::...:|.......|:|     |:.
Human   313 PKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT-EEAPLKLSKAVHKAVLTIDEKG-----TEA 371

  Fly   340 GNGSLTHTF-----NGVKYFLATHPFAFYIID-NT-SIYFAGHVTS 378
            .........     ..||:   ..||.|.:|: || |..|.|.|.:
Human   372 AGAMFLEAIPMSIPPEVKF---NKPFVFLMIEQNTKSPLFMGKVVN 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	76/367 (21%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	76/367 (21%)
		RCL	368..392		4/31 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010