Protein Alignment Spn53F and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 89/422 - (21%)
• Similarity: 176/422 - (41%)
• Gaps: 67/422 - (15%)

  Fly     1 MYVLLLILL----GISRYR---AQKNSQLPD-----------------ELYAAIVNSFSNRNIMF 41
            :::||.::|    |.|.:|   .:...::.|                 :||.|:.::..:::|.|
Human     3 LFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAAPSQSIFF 67

  Fly    42 STEMIRSSMLFIYVGVEEDESEQI------------RKAMHYRGTHLSEYKPKTQKIFAMSVKKA 94
            |...|..|:..:.:|.......||            .|.:|.....|.:...:.:..|.:|:..|
Human    68 SPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNA 132

  Fly    95 PVAKSLTRFYVRQNMKMSTEYRVFMRHT-EGRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKES 158
            .....:...   |:..:|....:::..| ....|:.|.|.:|   :|.:.:.:...:|..::|.
Human   133 LFTDLVVDL---QDTFVSAMKTLYLADTFPTNFRDSAGAMKQ---INDYVAKQTKGKIVDLLKN- 190

  Fly   159 WWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATA 223
             ...|:..::||.|||...||.:||.:.|..::|.|.:...|.:|||..:.::.:.:..||....
Human   191 -LDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRV 254

  Fly   224 VLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSVARNLTM-----MDVFVGIPKFKIHSDL 283
            |.||: .|:...|.|.|.:    ..:|.....::..::.:.|.|     ::::  :|||.|....
Human   255 VGVPY-QGNATALFILPSE----GKMQQVENGLSEKTLRKWLKMFKKRQLELY--LPKFSIEGSY 312

  Fly   284 ELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTF 348
            :|......:||.::|......|. :..::|.::..::|....|..|.|....:   ..|:: .||
Human   313 QLEKVLPSLGISNVFTSHADLSG-ISNHSNIQVSEMVHKAVVEVDESGTRAAA---ATGTI-FTF 372

  Fly   349 NGVKY----FLATHPFAFYIIDNTSIYFAGHV 376
            ...:.    .:...||..:|:|| :|.|.|.|
Human   373 RSARLNSQRLVFNRPFLMFIVDN-NILFLGKV 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	81/372 (22%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	81/379 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010