Protein Alignment Spn53F and SERPINB2

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_002566.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 94/406 - (23%)
• Similarity: 174/406 - (42%)
• Gaps: 59/406 - (14%)

  Fly    26 LYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQKIFAM- 89
            |:..:..:...:|:..|...|.|:|..:|:|......:|:.|.:.:.....:...|.|.:.|..
Human    15 LFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPENFTSC 79

  Fly    90 -------------SVKKAPVA-----------------------KSLTRFYVRQNMKMSTEY-RV 117
                         ::.:|..|                       :|:.:.:..::.....|| |:
Human    80 GFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRL 144

  Fly   118 FMRHTEGRARNIAF---AREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWE 179
            ..::.....:.:.|   |.|...::|::...:...:|..::.|.....:::.:||||::|...|:
Human   145 CQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWK 209

  Fly   180 RTFNPE--ATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQ 242
            ..|..:  ..||  ||||:.:...:.||:...|...|.:.:|||..:.:|:: ||:.|.|:.||:
Human   210 TPFEKKLNGLYP--FRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYA-GDVSMFLLLPDE 271

  Fly   243 ----PDGLAALQMKL--QAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIF-KP 300
                ..||..|:.::  ..:|..:....:...:|.|.||:||:....||......||::|.| |.
Human   272 IADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKG 336

  Fly   301 SKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLT-HTFNGVKYFLATHPFAFYI 364
            ..:||.:..||..| :..|.|....:..|:  ||.:.....|.:| .|.:|...|:|.|||.|.|
Human   337 RANFSGMSERNDLF-LSEVFHQAMVDVNEE--GTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLI 398

  Fly   365 IDNTS--IYFAGHVTS 378
            :...:  |.|.|..:|
Human   399 MHKITNCILFFGRFSS 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	94/406 (23%)
SERPINB2	NP_002566.1	serpinB2_PAI-2	2..415	CDD:381029	94/406 (23%)