DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Spn100A

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_651818.1	Gene:	Spn100A / 43642	FlyBaseID:	FBgn0039795	Length:	649	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	84/445 - (18%)
Similarity:	159/445 - (35%)	Gaps:	109/445 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YRAQKNSQLPDELYAAIVNSFSNRNIM------FSTEMIRSSMLFIYVGVEEDESEQIRKAMHYR 72
            :...|..:|.||...||.:....:.|:      |..::  ....::...|.:.|:|.::|....:
  Fly   189 FETLKRIKLDDEDIPAIPSDGYGQEIIDKEASKFDRDV--DDKQYVEKPVAQAEAELLQKEQKQQ 251

  Fly    73 GTHLSEYKPKTQKIFAMSVKKA----------PVAKSLTRFYVRQNMKMSTEYRVFMRHTEGRAR 127
            .|..||.:.:.::...:||:|.          |..|       :||.:...|        |.:.:
  Fly   252 ATTESELESQPEETTTLSVEKQEKPDMAAEENPAEK-------QQNKRSDQE--------ESQIK 301

  Fly   128 NI-----------------------------------------AFAREQLDE------------- 138
            |:                                         ..|::..||
  Fly   302 NLEENETVQEEEKLAKIMAAPALTAGEPEKVRLPLQKLENAVKTAAKDGADEIMLALESHLPSVS 366

  Fly   139 -VNTFYSHEMGEQIGQVVKESWWKPNSQG-----LLVNAIFFNLSWERTFNPEATYPREFRVNAT 197
             ||...|....:.|...:..:.....|.|     ||.|.:::..||...|........||.....
  Fly   367 RVNGARSLFQQDDITSALSANSITGRSAGSKSKMLLFNGLYYRGSWANPFYQLRDGSDEFFFMTN 431

  Fly   198 K-SVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSV 261
            : :|..||||...||....|..:||..:.:|:......:.::.||:.:||:.:..:||..:.|..
  Fly   432 EDAVKAPMMHARGKFQVADLPQVKARVLSLPYETSRYALCIVLPDETEGLSDVISQLQTSDFLLA 496

  Fly   262 ARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFE 326
            .:...|.::.:.:|||::..........::||:|.:|..:::..:||..:.:..:|.::..|...
  Fly   497 KKQFQMKELHISMPKFQVEETSRSEAMLKQMGLKKVFSRTEAQLSLLSEDPDVHVDEIVQFVNVR 561

  Fly   327 FQEQG-----IGTPSTDVGNGSLTHT----------FNGVKYFLATHPFAFYIID 366
            ..|.|     :...:......|:..|          ..||:.|....|||::|:|
  Fly   562 VDEGGSSANSLSAATMQARTPSVESTVLPVPEPEPELPGVERFEVNRPFAYFIVD 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	81/434 (19%)
Spn100A	NP_651818.1	SERPIN	41..>148	CDD:294093
Spn100A	NP_651818.1	SERPIN	<380..628	CDD:294093	53/237 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010