Protein Alignment Spn53F and SERPINA2

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 79/396 - (19%)
• Similarity: 150/396 - (37%)
• Gaps: 73/396 - (18%)

  Fly    20 SQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQ 84
            :.|..:||..:.:.....|::.:...:..:...:.:|.:.|...:|.:.::...|...|  .|..
Human    58 TDLAFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPE--AKIH 120

  Fly    85 KIFAMSVKKAPVAKSLTR------------FYVRQNMKMSTEY-----RVFMRHTEGRARNIAFA 132
            :.|..      |.::|:|            .:|.::||:...:     :::  |:|..:.|....
Human   121 ECFQQ------VLQALSRPDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLY--HSEASSINFRDT 177

  Fly   133 REQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNAT 197
            .|..:::|.:.....|.::..:||.  .|.::...||:.|.|:..|:..|..|......|.|:..
Human   178 EEAKEQINNYVEKRTGRKVVDLVKH--LKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDK 240

  Fly   198 KSVMIPM--------MHEDSKFAFGIL-----GNLKATAVLVPFSHGDLRMLLIKPDQPDGLAAL 249
            ..:.:||        :|.|.:.:..:|     ||  |||            ..|.|| |..:..|
Human   241 TIIRVPMINHLGRFDIHRDRELSSWVLAQHYVGN--ATA------------FFILPD-PKKMWQL 290

  Fly   250 QMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNF 314
            :.||...::.::.|...:..:.:..||..|....:|......:||..||......|. :.:....
Human   291 EEKLTYSHLENIQRAFDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNEADLSG-VSQEAPL 354

  Fly   315 RIDGVIHVVTFEFQEQG---IGTPSTDVGNGSLTHT--FNGVKYFLATHPFAFYIIDNTSIY--F 372
            ::...:||......|:|   .|.|..:....|...|  ||        .||...|.|:.:.:  |
Human   355 KLSKAVHVAVLTIDEKGTEATGAPHLEEKAWSKYQTVMFN--------RPFLVIIKDDITNFPLF 411

  Fly   373 AGHVTS 378
            .|.|.:
Human   412 IGKVVN 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	79/396 (20%)
SERPINA2	NP_006211.2	serpinA2_PIL	56..418	CDD:381018	79/396 (20%)