DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn53F and serpind1

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_878300.1	Gene:	serpind1 / 359841	ZFINID:	ZDB-GENE-030711-2	Length:	507	Species:	Danio rerio

Alignment Length:	403	Identity:	89/403 - (22%)
Similarity:	175/403 - (43%)	Gaps:	54/403 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LILLGISRYRAQK----NSQLPDELYAAIVNSFSNR-NIMFSTEMIRSSMLFIYVGVEEDESEQ- 64
            |:.|...:.|.|:    |::....||..:.|..:.. ||:.:...|..:|..:.:||..:..||
Zfish   121 LLRLFHGQTRLQRINVVNARFGFRLYRKLRNRLNQTDNILLAPVGISIAMGMMGLGVGPNTQEQL 185

  Fly    65 ---------IRKAMHYRGTHLSE-YKPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYRVFM 119
                     :..:.||..:.:.: ::..|.::|..:.  ....:|:...||::|:::...:|
Zfish   186 FQTVGFAEFVNASNHYDNSTVHKLFRKLTHRLFRRNF--GYTLRSVNDLYVKRNVQIQDSFR--- 245

  Fly   120 RHTEGRARNIAFAREQ-LDEVNTFYSHEMGEQIGQV----VKESWWK--PNSQGLLVNAIFFNLS 177
                ..|:...||..| :|..:..:..:..::|.::    :||....  ||...:|:|.::|..:
Zfish   246 ----ADAKTYYFAEPQSVDFADPAFLVKANQRIQKITKGLIKEPLKSVDPNMAVMLLNYLYFKGT 306

  Fly   178 WERTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQ 242
            ||:.|..|.|:.|:||||..|.|.:.||.....:.......|....:.:|:: |::.||:..|.:
Zfish   307 WEQKFPKELTHHRQFRVNEKKQVRVLMMQNKGSYLAAADHELNCDILQLPYA-GNISMLIAVPQK 370

  Fly   243 PDGLAALQMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTL 307
            ..|:.:|:.::....:.....|:|.....|..|:||:..:.:|....::||:.|||.....||.:
Zfish   371 LSGMRSLEQEISPTLVNKWLSNMTNRTREVVFPRFKLEQNYDLIEHLKEMGMTDIFTEKGDFSPM 435

  Fly   308 LHRNTNFRIDGVIHVVTFEFQEQG---IGTPSTDVGNGSLTH----TFNGVKYFLATHPFAFYII 365
            ....          |:...|:.||   :....|:.  .::||    ..:....|:...||.|.|.
Zfish   436 TSEK----------VIINWFKHQGSITVNEEGTEA--AAMTHIGFMPLSTQTRFIVDRPFLFLIY 488

  Fly   366 DNTS--IYFAGHV 376
            ::.:  :.|.|.|
Zfish   489 EHRTGCVVFMGRV 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	83/378 (22%)
serpind1	NP_878300.1	HCII	61..505	CDD:239002	89/403 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.110