DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinc1

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001012027.1	Gene:	Serpinc1 / 304917	RGDID:	1307404	Length:	465	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	94/423 - (22%)
Similarity:	159/423 - (37%)	Gaps:	106/423 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFS-NRNIMFSTEMIRSSMLFIYVG-----------------VEEDES 62
            ::.||:.....|..:.:|.: |.||..|...|.::.....:|                 :.|..|
  Rat    85 SKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNNTLKQLMEVFKFDTISEKTS 149

  Fly    63 EQIR------KAMHYRGTHLSEYKPKTQKIFA----------MSVKKAPVAKSLTRFYVRQNMKM 111
            :||.      ....||..:.|.......::|.          ..|.:......|.....::|.:.
  Rat   150 DQIHFFFAKLNCRLYRKANKSSNLVSANRLFGDKSLTFNESYQDVSEIVYGAKLQPLDFKENPEQ 214

  Fly   112 STEYRVFMRH-----TEGRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNA 171
            |   ||.:.:     ||||.::: ..:..:||:...                        :|||.
  Rat   215 S---RVTINNWVANKTEGRIKDV-IPQGAIDELTAL------------------------VLVNT 251

  Fly   172 IFFNLSWERTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVL-VPFSHGDLRM 235
            |:|...|:..|:||.|....|.....:|.::|||:::.||.:..:|  :.|.|| :||...|:.|
  Rat   252 IYFKGLWKSKFSPENTRKEPFHKVDGQSCLVPMMYQEGKFKYRRVG--EGTQVLEMPFKGDDITM 314

  Fly   236 LLIKPDQPDGLAALQMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKP 300
            :||.|.....||.::.:|....:......|:.:.:.|.:|:|:|.....|....:.||:.|:|.|
  Rat   315 VLILPKPEKSLAKVEQELTPELLQEWLDELSEVMLVVHVPRFRIEDSFSLKEQLQDMGLVDLFSP 379

  Fly   301 SKSFSTLLHRNTNFRIDGVI-------------HVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVK 352
            .||           ::.|:|             |....|..|:|    |....:.|:..|...:.
  Rat   380 EKS-----------QLPGIIAEGRDDLFVSDAFHKAFLEVNEEG----SEAAASTSVVITGRSLN 429

  Fly   353 ----YFLATHPFAFYIID---NTSIYFAGHVTS 378
                .|.|..||...|.:   || |.|.|.|::
  Rat   430 PSRVTFKANRPFLVLIREVALNT-IIFMGRVSN 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	91/410 (22%)
Serpinc1	NP_001012027.1	antithrombin-III_like	80..459	CDD:239000	93/419 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030