DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and LOC299282

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001376144.2	Gene:	LOC299282 / 299282	RGDID:	3745	Length:	413	Species:	Rattus norvegicus

Alignment Length:	435	Identity:	92/435 - (21%)
Similarity:	148/435 - (34%)	Gaps:	141/435 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTH----- 75
            |..|:.....||..:.....::|::||...|.:::..:.:|.::...|:|.:.:.:..|.
  Rat    46 ASSNTDFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEEE 110

  Fly    76 -----------------------------------LSEYKPKTQKI-----FAMSVKKAPVAKSL 100
                                               |||::.||:.:     |....|:...||.|
  Rat   111 IHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKL 175

  Fly   101 TRFYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQ 165
            ...||             ...|:|:   ||.....|:|                        .:.
  Rat   176 INDYV-------------SNQTQGK---IAELFSDLEE------------------------RTS 200

  Fly   166 GLLVNAIFFNLSWERTFNPEATYPREFRVNATKSVMIPMMH---------EDSKFAFGILGNLKA 221
            .:|||.:.|...|:..|||..|:..||.::..:||.:|||.         .|.:.:..:| .||.
  Rat   201 MVLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKIKEVTTPYVRDEELSCSVL-ELKY 264

  Fly   222 TAVLVPFSHGDLRMLLIKPD-----------QPDGLAALQMKLQAMNILSVARNLTMMDVFVGIP 275
            |        |:...|.|.||           ||:.|...:..|    |..:..:|.|       |
  Rat   265 T--------GNASALFILPDQGKMQQVESSLQPETLKKWKDSL----IPRIINDLRM-------P 310

  Fly   276 KFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGI-GTPSTDV 339
            ||.|.:|..|.....::|||.:|......|.:. ...:..:..|:|....:..|.|. .|.:|.|
  Rat   311 KFSISTDYSLKEVLPELGIKKVFSQQADLSRIT-GTKDLYVSQVVHKAVLDVDETGTEATAATGV 374

  Fly   340 G----NGSLTHTFNGVKYFLATHPFAFYI--IDNTSIYFAGHVTS 378
            .    ....|..||        .||...|  :|:.||.|...:|:
  Rat   375 ATVIRRQPRTLNFN--------RPFMVVITDMDSQSILFVAKITN 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	89/422 (21%)
LOC299282	NP_001376144.2	serpinA3_A1AC	36..413	CDD:381019	92/435 (21%)
LOC299282	NP_001376144.2	RCL	365..389		7/31 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010