DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serping1

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_954524.1	Gene:	Serping1 / 295703	RGDID:	735225	Length:	504	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	72/380 - (18%)
Similarity:	141/380 - (37%)	Gaps:	65/380 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 ELYAAI-VNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEYKPKTQKIFA 88
            :||.|. ....:..|:.||...|.|.:..:.:|..:.....:...:.|         ||.   ||
  Rat   157 KLYHAFSATKKAETNMAFSPFSIASLLTQVLLGAGDSTKSNLEDILSY---------PKD---FA 209

  Fly    89 M--SVKKAPVAKSLTRF--------------YVRQNMKM-STEYRVFMRHTEGRARNIAFAREQL 136
            .  ...||..:|.:|..              ||..::.: .:..||.  ..:|.|        .|
  Rat   210 CVHQTLKAFSSKGVTSVSQIFHSPDLAIRDTYVNASLSLYGSSPRVL--GPDGDA--------NL 264

  Fly   137 DEVNTFYSHEMGEQIGQVVKESWWKPNSQGL-LVNAIFFNLSWERTFNPEATYPREFRVNATKSV 200
            ..:||:.:.....:|.:::..   .|:...| |:||::.:..|::||..:.........|:  .:
  Rat   265 KLINTWVAENTNHKINELLDS---LPSDTRLVLLNAVYLSAKWKKTFEQKKMMASFLYKNS--MI 324

  Fly   201 MIPMMHEDSKFAFGILGN--LKATAVLVPFSHGDLRMLLIKPDQP-DGLAALQMKLQAMNILSVA 262
            .:||: ...|:...:..:  |||....:..|| :|..:::.|..| ..|..::..|......::.
  Rat   325 KVPML-SSKKYPLALFNDQTLKAKVGQLQLSH-NLSFVIMVPQSPTHQLEDMEKALNPTVFKAIL 387

  Fly   263 RNLTM---MDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTL-LHRNTNFRIDGVIHVV 323
            :.|.:   ...:|.:|:.|:.|..::....||:   :.|..:...:.. |..:.:.::..:.|..
  Rat   388 KKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKL---EFFDFTYDLNLCGLTEDPDLQVSSMKHET 449

  Fly   324 TFEFQEQGIGTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIIDNTSIY--FAGHV 376
            ..|..|.|:     :....|.......:..|....||.|.:.|....:  |.|.|
  Rat   450 VLELTETGV-----EAAAASTISVARNLLIFEVQQPFLFLLWDQRHKFPVFMGRV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	71/378 (19%)
Serping1	NP_954524.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..132
		SERPIN	150..499	CDD:294093	71/378 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100