Protein Alignment Spn53F and SERPINA11

DIOPT Version :10

• Sequence 1: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 85/375 - (22%)
• Similarity: 148/375 - (39%)
• Gaps: 62/375 - (16%)

  Fly    38 NIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSE------YKPKTQKIFAMSVK-KAP 95
            ||.||...|.:::..:.:|.:.:.|..|.:.:.:..|...|      ::.....:...|.| :..
Human    72 NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLALPSPKLELK 136

  Fly    96 VAKSLTRFYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYSHEMGEQI--------- 151
            |..||   ::.:.:|....|...::...|.   .||:....|.|.|      |.||
Human   137 VGNSL---FLDKRLKPRQHYLDSIKELYGA---FAFSANFTDSVTT------GRQINDYLRRQTY 189

  Fly   152 GQVV---KESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPRE-FRVNATKSVMIPMMHEDSKFA 212
            ||||   .|  :..::..:|.|.|||...|:..|:...|..:| |.|:...|:.:||||:.....
Human   190 GQVVDCLPE--FSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHR 252

  Fly   213 FGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSVARNL--TMMDVFVGIP 275
            |....:|..|.:.:.: .|:...||:.|| |..:..::..||...:....:.|  :::|:.  :|
Human   253 FLYDQDLACTVLQIEY-RGNALALLVLPD-PGKMKQVEAALQPQTLRKWGQLLLPSLLDLH--LP 313

  Fly   276 KFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHVVTFEFQEQGIGT------ 334
            :|.|.....|.....::|:.:|......||.:..: .|..|..|.|....:..|:|...
Human   314 RFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQ-LNKTISKVSHKAMVDMSEKGTEAGAASGL 377

  Fly   335 ----PSTDVGNGSLTHTFNGVKYFLATHPFAFYI--IDNTSIYFAGHVTS 378
                ||.:..:....| ||        .||...:  :...|:.|.|.|.:
Human   378 LSQPPSLNTMSDPHAH-FN--------RPFLLLLWEVTTQSLLFLGKVVN 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	85/375 (23%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	85/375 (23%)