DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpina4

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_659565.2	Gene:	Serpina4 / 246328	RGDID:	708581	Length:	423	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	95/395 - (24%)
Similarity:	157/395 - (39%)	Gaps:	44/395 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ISRYR-AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGT 74
            ||.|: |..|:.....||..|.:..|.:||.||...|..|:..:..|...|...||.:.:.:..|
  Rat    43 ISSYQIASGNANFAFRLYHLIASQNSEKNIFFSPLSISVSLAILSTGAGGDTQAQILEGLGFNLT 107

  Fly    75 HLSEYKPKTQKIFAMSVKKAPVAKSLTR--------FYVRQNMK--------MSTEYRVFMRHTE 123
            .||  .|:..:.| .|::.. :|:..|.        ..:.||::        :.|.|...:.|..
  Rat   108 KLS--LPEIHEGF-RSLQHT-IARPFTEPQISVGSALILSQNLQILSEFVSAIETSYNSKVLHAN 168

  Fly   124 GRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATY 188
            .|.:..|.   ||  :|.:.......:|..:|.:  ..|:.:.:|||.|||...|::.|......
  Rat   169 FRDKEAAV---QL--INNYVKQNTQGKIKNLVSD--LSPDVKMVLVNYIFFQGLWKKPFPSSRVS 226

  Fly   189 PREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQ-----PDGLAA 248
            ..:|.|:....|.||||.:|.:..:.:........||.....||.....|.|||     .:.:.:
  Rat   227 TSDFYVDENTVVKIPMMLQDKEDHWYLEDRRVPCTVLRMDYRGDAVAFFILPDQGKMNEVEQVLS 291

  Fly   249 LQMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTN 313
            ..|.|:...:|.  .......:.:.:|||.|.:..||......:|.:|:|.|:.:||. :.:...
  Rat   292 PGMLLRWKRLLQ--NRFFYRKLILQLPKFSISNSYELDEILPDLGFQDLFTPNANFSN-ISKKEK 353

  Fly   314 FRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNG---VKYFLATHPF--AFYIIDNTSIYFA 373
            ..:..|.|....:..|  :||.:. ...||....|:.   .:|.:...||  ..|...:..|.|.
  Rat   354 LYLSKVFHKTVLDVNE--VGTKAA-AATGSFATFFSAQPKKRYLIFNRPFLVILYSTSSQDILFM 415

  Fly   374 GHVTS 378
            |.|.:
  Rat   416 GKVVN 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	89/376 (24%)
Serpina4	NP_659565.2	SERPIN	52..418	CDD:294093	90/382 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110