DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_035590.1	Gene:	Serpinb9d / 20726	MGIID:	894667	Length:	377	Species:	Mus musculus

Alignment Length:	399	Identity:	85/399 - (21%)
Similarity:	172/399 - (43%)	Gaps:	63/399 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMH-------YRG 73
            :|.|......|...:.....:.|:.||...|.|::..:.:|.:.:...||.:|:|       ::|
Mouse     5 SQANGTFAIHLLKVLCQDNPSENVCFSPMSISSALAMVLLGAKGNTVTQICQALHLNPDEDVHQG 69

  Fly    74 THLSEY---KPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYR---VFMRHTEGRARNIA-F 131
            ..|..:   ||..|| :.:::        ..|.:|....::...::   :...|:|....:.| .
Mouse    70 FQLLLHNLNKPNNQK-YCLTM--------ANRLFVENTCELLPTFKESCLKFYHSEMEQLSFAEA 125

  Fly   132 AREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRVNA 196
            |.|....:|.:.|.:...:|..::.:......::.:|.||::|..:|.:.|..::|....|::|.
Mouse   126 AEESRQHINMWVSKQTNGKIPDLLPKDSIDSQTRLILANALYFQGTWYKLFEKDSTKEMPFKINK 190

  Fly   197 TKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILSV 261
            .::..:.||.::.:|....:..::|..:::|:...||..:::.||            :.::|..|
Mouse   191 KETRPVQMMWQEDRFYHAYVKEIQAQVLVMPYEGIDLSFVVLLPD------------KGVDISKV 243

  Fly   262 ARNLTM--------------MDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNT 312
            ..|||.              :::.|.:|||::..|.:::...:.:||.|:|..||:..:.:....
Mouse   244 ENNLTFEKLTAWTKPDFMNGIELHVYLPKFQLQEDYDMNSLLQHLGILDVFDGSKADLSGMSTKE 308

  Fly   313 NFRIDGVIHVVTFEFQEQGIGTPSTDVGN------GSLTHTFNGVKYFLATHPFAFYIIDNT--S 369
            |..:...:|....|..|:|....:...|.      ||...|      |.|.|||.|:|:.:|  |
Mouse   309 NLCLSNFVHKCVVEVNEEGTEAAAATAGKTIQCCLGSYPQT------FCADHPFLFFIMHSTTNS 367

  Fly   370 IYFAGHVTS 378
            |.|.|..:|
Mouse   368 ILFCGRFSS 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	82/386 (21%)
Serpinb9d	NP_035590.1	serpin	1..377	CDD:393296	85/399 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830