DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinb9f

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_899020.1	Gene:	Serpinb9f / 20709	MGIID:	894671	Length:	377	Species:	Mus musculus

Alignment Length:	406	Identity:	81/406 - (19%)
Similarity:	167/406 - (41%)	Gaps:	77/406 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMH-------YRG 73
            :|.|......|...:.....::|:.:|...|.|::..:.:|.:.|.:.||.:|:|       ::|
Mouse     5 SQANGTFAIHLLKVLCQDNPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALHLNPDEDVHQG 69

  Fly    74 THLSEY---KPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYR---VFMRHTEGRARNIAFA 132
            ..|..:   |...||.         ..:...|.:|....::...::   :...|:|  ...::||
Mouse    70 FQLLLHNLNKQNNQKY---------CLRMANRLFVENTCELLPTFKESCLKFYHSE--MEQLSFA 123

  Fly   133 R---EQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNPEATYPREFRV 194
            :   |....:|.:.|.:...:|..::.:......::.:|.||::|:.:|.:.|....|....|::
Mouse   124 KAAEESRQHINMWVSKQTNGKIPDLLSKDSVNSQTRLILANALYFHGTWCKRFEKNRTKEMPFKI 188

  Fly   195 NATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNIL 259
            |..::..:.||..:.......:..::|..:::|:...||..:::.||            :.::|.
Mouse   189 NKKETRPVQMMWREDTLFHAYVKEIQAQVLVMPYEGIDLNFVVLLPD------------EGVDIS 241

  Fly   260 SVARNLTM--------------MDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHR 310
            .|..|||.              .:..|.:|||::..|.:::...:.:||.::|..||:..:.:..
Mouse   242 KVENNLTFEKLTAWTKPEFMNRTEFHVYLPKFQLQEDYDMNSLLQHLGILNVFDGSKADLSGMST 306

  Fly   311 NTNFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVKY-----------FLATHPFAFYI 364
            ..|..:...:|....|..|:|     |:....|      .|::           |.|.|||.|:|
Mouse   307 KENLCLSEFVHKCVVEVNEEG-----TEAAAAS------AVEFIFLCLGPDPETFCADHPFLFFI 360

  Fly   365 IDNT--SIYFAGHVTS 378
            :.:|  ||.|.|..:|
Mouse   361 MHSTTNSILFCGRFSS 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	78/393 (20%)
Serpinb9f	NP_899020.1	SERPIN	4..377	CDD:294093	81/406 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830