DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinf1

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_035470.3	Gene:	Serpinf1 / 20317	MGIID:	108080	Length:	417	Species:	Mus musculus

Alignment Length:	382	Identity:	82/382 - (21%)
Similarity:	163/382 - (42%)	Gaps:	43/382 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QLPDELYAAIVNSFS------------NRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHY-- 71
            ::|....||.|::|.            ..|::.|...:.:::..:.:|.|......|.:|::|
Mouse    47 KVPVNKLAAAVSNFGYDLYRLRSSASPTGNVLLSPLSVATALSALSLGAEHRTESVIHRALYYDL 111

  Fly    72 ---RGTHLSEYKPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYRVFMRHTEGRARNIAFA- 132
               ...| |.||    ::.|.........||.:|....:.:::.:.:...:..:.|....|...
Mouse   112 ITNPDIH-STYK----ELLASVTAPEKNLKSASRIVFERKLRVKSSFVAPLEKSYGTRPRILTGN 171

  Fly   133 -REQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQG-LLVNAIFFNLSWERTFNPEATYPREFRVN 195
             |..|.|:|.:...:|..:|.:..:|   .|::.. ||:...:|...|...|:...|..::|.::
Mouse   172 PRVDLQEINNWVQAQMKGKIARSTRE---MPSALSILLLGVAYFKGQWVTKFDSRKTTLQDFHLD 233

  Fly   196 ATKSVMIPMMHEDSK--FAFGILGNLKATAVLVPFSHGDLRMLLIKP-DQPDGLAALQMKLQAMN 257
            ..::|.:||| .|.|  ..:|:..:|......:|.: |.:.::...| .....|..::..|.:..
Mouse   234 EDRTVRVPMM-SDPKAILRYGLDSDLNCKIAQLPLT-GSMSIIFFLPLTVTQNLTMIEESLTSEF 296

  Fly   258 ILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVIHV 322
            |..:.|.|..:...:.:||.|:..:.||:.:.:.|.::.:|: |..||.:..:..  ::..|.|.
Mouse   297 IHDIDRELKTIQAVLTVPKLKLSFEGELTKSLQDMKLQSLFE-SPDFSKITGKPV--KLTQVEHR 358

  Fly   323 VTFEFQEQGIG-TPSTDVGNGSLTHTFNGVKYFLATHPFAFYI--IDNTSIYFAGHV 376
            ..||:.|:|.| :||..:....||...:   |.| ..||.|.:  .|..::.|.|.:
Mouse   359 AAFEWNEEGAGSSPSPGLQPVRLTFPLD---YHL-NQPFLFVLRDTDTGALLFIGRI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	81/376 (22%)
Serpinf1	NP_035470.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..41
Serpinf1	NP_035470.3	PEDF	39..414	CDD:239007	82/382 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100