DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn53F and Serpinb7

DIOPT Version :9

Sequence 1:	NP_001036553.1	Gene:	Spn53F / 36931	FlyBaseID:	FBgn0034195	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_081824.1	Gene:	Serpinb7 / 116872	MGIID:	2151053	Length:	380	Species:	Mus musculus

Alignment Length:	391	Identity:	89/391 - (22%)
Similarity:	168/391 - (42%)	Gaps:	46/391 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQKNSQLPDELYAAIVNSFSNRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHY----RGTHL 76
            |..|::...:|:..:.:|..|.|:.||:..|.:::..|.:|...|.:.||.||:|:    |..:.
Mouse     5 AAANAEFGFDLFREMDSSQGNGNVFFSSLSIFTALTLIRLGARGDCARQIDKALHFNIPSRQGNS 69

  Fly    77 SEYKPKTQ--------------KIFAMSVKKAPVAKSLTRF---YVR--QNMKMSTEYRVFMRHT 122
            |..:|..|              |.:.:|:.....|:.:..|   |:.  :|:            .
Mouse    70 SNNQPGLQYQLKRVLADINSSHKDYELSIATGVFAEKVYDFHKNYIECAENL------------Y 122

  Fly   123 EGRARNIAFAREQLD---EVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWERTFNP 184
            ..:...:.|..:..|   ::|.:..:|...:|.:|:.:|....::..:||||::|...|:..|..
Mouse   123 NAKVERVDFTNDVQDTRFKINKWIENETHGKIKKVLGDSSLSSSAVMVLVNAVYFKGKWKSAFTK 187

  Fly   185 EATYPREFRVNATKSVMIPMMHEDSKFAFGILGNLKATAVLVPFSHGDLRMLLIKPDQPDGLAAL 249
            ..|....||.......::.|||::.:|....:.......:.:.: ||.:.|.::.|:  |||..:
Mouse   188 TDTLSCRFRSPTCPGKVVNMMHQERRFNLSTIQQPPMQVLELQY-HGGISMYIMLPE--DGLCEI 249

  Fly   250 QMKLQAMNILSVARNLTMMDVFVGI--PKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNT 312
            :.||...|::.......|...:|.:  |:|||..:.|::...:.:|:||||..|.:..:.:....
Mouse   250 ESKLSFQNLMDWTNRRKMKSQYVNVFLPQFKIEKNYEMTHHLKSLGLKDIFDESSADLSGIASGG 314

  Fly   313 NFRIDGVIHVVTFEFQEQGI-GTPSTDVGNGSLTHTFNGVKYFLATHPFAFYIIDNTSIYFAGHV 376
            ...:..::|....|..|:|. .|.:|:  |..:.........|.|..||.|.|..|..|.|.|.|
Mouse   315 RLYVSKLMHKSFIEVSEEGTEATAATE--NNIVEKQLPESTVFRADRPFLFVIKKNDIILFTGKV 377

  Fly   377 T 377
            :
Mouse   378 S 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	86/379 (23%)
Serpinb7	NP_081824.1	SERPIN	4..380	CDD:294093	89/391 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930