Protein Alignment CG15611 and GEFmeso

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_788403.2
• Gene: GEFmeso / 37134
• FlyBaseID: FBgn0050115
• Length: 1549
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 127/549 - (23%)
• Similarity: 218/549 - (39%)
• Gaps: 154/549 - (28%)

  Fly     7 TLNLFDVVSVVLTFLVIFLVQILNVYLHILDDNADNG------KSIDVVDKAPAKECPLLESQSP 65
            |:| ||:|:..:..|.:                ||.|      :.|:.|:|....: ||:.|.|.
  Fly   361 TIN-FDLVAQHMERLTL----------------ADPGDLDPRAELIEAVNKTLVNK-PLVRSSSA 407

  Fly    66 -------SSPIAT-TLPKS---QASSNG-----KL--EKQISLLDSDSGIS-------------- 98
                   |||:.| ...||   :||:.|     ||  .:|::.|:..:.:|
  Fly   408 ACASTICSSPLLTYARTKSLGAKASTLGGGVPIKLPTAEQLAELEEANKLSAESLDRLTDIKPKF 472

  Fly    99 --------------LSSINTCSTTAANSSPTYRAPNGFHSFPSHTLSFETLGDEYHEDEDTLSLE 149
                          |||.:.|||::::||.:.:..||.....|:..|.|:|.    |.|:.|.
  Fly   473 AARLSELARLNNRPLSSSSICSTSSSSSSGSDQLLNGKLMATSYLASVESLA----ESENELG-- 531

  Fly   150 NLFPCDQTEIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLG 214
                 ||....|...:.....|::.:|.::|.:|  |.:..|.|:|.::  .|.....:.::|..
  Fly   532 -----DQHHPPAMSVLEKTCLEIVDSERSFVEDL--GQVIKGYLQDWKE--RACLRVDELQILFA 587

  Fly   215 NIKEILELHEKEILPLMLRNQRD---LKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRL 276
            ||:||.|.:.. :|..::...||   :...|.:....|:..:.|| .|:........:|.|....
  Fly   588 NIEEIYEFNSM-LLQRLINTGRDPGRIARCFIDLRDGFDVYTTYC-TSYPEAISLLTKLLQATHT 650

  Fly   277 W--LQTYQTQIKDKLGIDSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTAVCKLETRMRR 339
            :  |.:.|..::.:|.:.|:|::|:||:.:|.|||...     :.....|.|:.|    ...||:
  Fly   651 YSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSL-----RKHCDVKEVVEA----HVIMRQ 706

  Fly   340 ALDVVNQA----EEIPNIEELN---------ELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLF 391
            ....::|.    |:...::||:         ||.|  ||..|:......||...|     .|.||
  Fly   707 VAHNIDQVKRKQEQQSRVKELSGILDGWLGPELTV--LGELRQEGLLMEQHNKQR-----LVLLF 764

  Fly   392 DRCLVCTEVRKK-RLAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSF 455
            ...|:.|:.::. ||.::.:              :|.|     ||::.:...|       |..||
  Fly   765 ATMLIITKQKEDGRLQFKTY--------------ISQN-----NLMLSEHLPG-------EPTSF 803

  Fly   456 MAAEASVVKQWLQATHKIIEIARNEHARR 484
                  .|..:.:..|:|...|||...:|
  Fly   804 ------YVIPFDEPRHQIKLTARNRDQKR 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	37/150 (25%)
GEFmeso	NP_788403.2	RhoGEF	548..712	CDD:459876	42/178 (24%)
		PH_PLEKHG1_G2_G3	694..839	CDD:270063	40/176 (23%)