Protein Alignment CG15611 and Arhgef40

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_038949404.1
• Gene: Arhgef40 / 361034
• RGDID: 1308093
• Length: 1520
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 99/548 - (18%)
• Similarity: 175/548 - (31%)
• Gaps: 175/548 - (31%)

  Fly    57 CPLLESQSPSSP---IATTLPKSQASSNGKLEKQISL-LDSDSGISLSSINTCSTTA-------- 109
            |..|....|...   .|..|.::...|.|..::..:| ||..|..:|.....|....
  Rat   886 CARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCRARCQELERRIQ 950

  Fly   110 ----------------ANSSPTYRAPNGFHS------------------FPSHTLSFETLGDEYH 140
                            |:|:.:..|.:|.||                  .||| .|....|::|.
  Rat   951 QQLGEEASPRSHRRRRADSASSAGAQHGAHSPSPSLSSLLLPSSPGPRAAPSH-CSLTPCGEDYE 1014

  Fly   141 EDEDTLSLE-----------------NLFPCDQT------------------------EIYASKK 164
            |:...|:.|                 :....|:|                        .:...:.
  Rat  1015 EEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRS 1079

  Fly   165 ISF---IIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPE-----------ALSGETKQKMLLGN 215
            ||.   ::.|||..|..|:..|.:.:...|        ||           |||...:.:...|.
  Rat  1080 ISAQQRLVSELIDCEQEYITTLNEPVPPPG--------PELTPGLRCTWAAALSVRERLRSFHGT 1136

  Fly   216 --IKEI--LELHEKEILPLMLRNQRDLKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRL 276
              ::|:  ...|...|....||: .|...|:.:|..|..|.. ....:.|...|.||:
  Rat  1137 HFLQELQGCTAHPLRIGACFLRH-GDQFNLYAQFVKHRHKLE-SGLTALTPSVKGSME------- 1192

  Fly   277 WLQTYQTQIKDKLG---IDSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTAVCKLETRMR 338
                         |   :...|.||:::|.||..||::.:.|       ..|.|::.   ...:|
  Rat  1193 -------------GSPCLPRALQQPLEQLARYAQLLEELLRE-------AGPELSSE---RQALR 1234

  Fly   339 RALDVVNQAE----EIPNIEELN--ELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLFDRCLVC 397
            .|:.::.:.|    ::..:|.:.  |:|:.:.|.......|..  ...|||....||||:..|:.
  Rat  1235 AAVQLLQEQEARGRDLLAVEAVRGCEIDLREQGQLLHRDPFTV--ICGRKKCLRHVFLFEDLLLF 1297

  Fly   398 TEVR-----KKRLAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFMA 457
            ::.:     .:...|:|.:....:.|...:    .::.....|..::...       ||.|:..|
  Rat  1298 SKSKGSEGGSETFVYKQAFKTADMGLTENI----GDSGLCFELWFRRRRA-------REAYTLQA 1351

  Fly   458 AEASVVKQWLQATHKII--EIARNEHAR 483
            .......:|..:..:::  :.|.|:..|
  Rat  1352 TSPETKLKWTSSIAQLLWRQAAHNKELR 1379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	36/166 (22%)
Arhgef40	XP_038949404.1	PHA03247	<251..446	CDD:223021
		SPEC	789..967	CDD:413338	13/80 (16%)
		RhoGEF	1087..1242	CDD:459876	41/194 (21%)
		PH_puratrophin-1	1241..1376	CDD:270062	24/147 (16%)