Protein Alignment CG15611 and Vav

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001097030.1
• Gene: Vav / 32920
• FlyBaseID: FBgn0040068
• Length: 1001
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 104/527 - (19%)
• Similarity: 199/527 - (37%)
• Gaps: 151/527 - (28%)

  Fly    45 SIDVVDK---------APAKECPLLESQSPSSPIATTLPKSQASS--NGKLEKQISLLDSDSGIS 98
            ::|||..         .|..|....:||||.:..|.::|.|.|..  .|:|            :|
  Fly   262 ALDVVSSTTDGASNAVTPTPESYARQSQSPLAAAAPSVPVSAAPGPPMGRL------------VS 314

  Fly    99 LSSINTCSTTAANSSPTYRAPNGFHSFPSHTLSFETLGDEY---HEDEDTLSLENL--------- 151
            .|| ::.|...:.|....||....:::.|...|.|   .||   :.::|....|:|
  Fly   315 TSS-SSSSLLVSESQRLQRAAAAVYNYRSSMASTE---HEYAYIYSEDDEKVYEDLCYVTFQAKA 375

  Fly   152 --------FPCDQT----------EIY------------------ASKKISFIIDELIQTEVNYV 180
                    ..|:.|          |:|                  :.::..::|.|||.||.||:
  Fly   376 KPEVTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYL 440

  Fly   181 NNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIKEILELHEK---EILPLMLRNQR-DLKGL 241
            :     :|...:.|.:..|...|: :.:.:::...|:|::::|.|   ::...:..|.: .:..:
  Fly   441 D-----VLTALKTKFMGPLERHLN-QDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQV 499

  Fly   242 FDEFAAHFEKNSFYCYVSFTMG---------KKSSM--QLRQDNRLWLQTYQTQIKDKLGIDSFL 295
            |.:|...|.....:|  |..:|         ||:.:  ||.|.........:.|::|.|.:
  Fly   500 FLDFREPFLIYGEFC--SLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSV---- 558

  Fly   296 VQPIQRLTRYPLLLQQFISEF------YKSGISCKPVLTAVCKLETRMRRALD---VVNQAE--- 348
              |:||:.:|.|||.:.:.|.      |:|....|..:..|.:....::|..|   ::.:.:
  Fly   559 --PMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSI 621

  Fly   349 -EIPNIEELNELDVLQLGNFRRATEFDAQHFPTRKKYRSKV---FLFDRCLVCT-----EVRKKR 404
             :|..::..|..|:||.|......|.   |....:..::|:   |:||:.|:..     :....:
  Fly   622 CDIHLLQNGNGSDLLQYGRLLLDGEL---HIKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQ 683

  Fly   405 LAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVG-SKREEYSFMAAEAS---VVKQ 465
            ..||..:|                   :.:..|:|.....::| ..|.:|..:.|..|   ....
  Fly   684 YTYRDSHN-------------------LADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTL 729

  Fly   466 WLQATHK 472
            :|::.|:
  Fly   730 YLKSEHE 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	38/160 (24%)
Vav	NP_001097030.1	CH_VAV	19..135	CDD:409050
		RhoGEF	428..602	CDD:459876	43/187 (23%)
		PH_Vav	624..753	CDD:269930	25/135 (19%)
		C1_VAV	759..810	CDD:410360
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:473055