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Protein Alignment CG15611 and TIAM2

DIOPT Version :10

Sequence 1:	NP_611189.2	Gene:	CG15611 / 36930	FlyBaseID:	FBgn0034194	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_036586.3	Gene:	TIAM2 / 26230	HGNCID:	11806	Length:	1701	Species:	Homo sapiens

Alignment Length:	571	Identity:	111/571 - (19%)
Similarity:	192/571 - (33%)	Gaps:	201/571 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ELSLFTLNLFDV----VSVVLTFLVIFLVQI------LNVYL-HILDDNAD-------------- 41
            |:.:|.||::||    ...|..|......|:      ..::: .:|.|...
Human   880 EIEVFPLNVYDVQLTKTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGLRKGNEIMTL 944

  Fly    42 NGKSIDVVD-------------------KAPAKECPLLESQSPSSPIA----TTLPKSQASSNGK 83
            ||:::..:|                   :.|..:..|..|.|.|...:    :.||....|.  .
Human   945 NGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKATLCTSWSDSDLFSRDQKSLLPPPNQSQ--L 1007

  Fly    84 LEKQISLLDSDSGISLSSINTCSTTAANSSPTYRAPNGFHSFPSHTLSFETLGDEYHEDEDTLSL 148
            ||:.:.....::....|::... ||....|.|    :|.....||.   |.:...:...|...:|
Human  1008 LEEFLDNFKKNTANDFSNVPDI-TTGLKRSQT----DGTLDQVSHR---EKMEQTFRSAEQITAL 1064

  Fly   149 ----------------ENLFPCDQT---EIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLK 194
                            ||..|..::   .:..:.::..:|.||:.||.:||             |
Human  1065 CRSFNDSQANGMEGPRENQDPPPRSLARHLSDADRLRKVIQELVDTEKSYV-------------K 1116

  Fly   195 DVEDL----PEALSGET-----KQKMLLGNIKEILELHEKEILPLMLRNQRD------------- 237
            |:..|    .|.|..||     :.:.|.|::.|:||..:     :.|....|
Human  1117 DLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQK-----VFLETLEDGISASSDFNTLET 1176

  Fly   238 ----------LKGLFDEFAAHFEKNSFYCYVSFTMGK-----------KSSMQLRQDNRLWLQTY 281
                      |.|.|..:|.||:..|.:|.....:.|           |:.:..|...:....|
Human  1177 PSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSST- 1240

  Fly   282 QTQIKDKLGIDSFLVQPIQRLTRYPLLLQQFIS-------EFYKSGISCKPVLTAVCKLETRMRR 339
                     ::|:|::|:||:.:|||||::.:|       |.|.        ||...|   .|.:
Human  1241 ---------LESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYH--------LTEALK---AMEK 1285

  Fly   340 ALDVVNQAEEIPNIEE----LNELDVLQLGNFRRATEFDAQHF----------------PTRKKY 384
            ....:|:.::|  .|:    .::|...|.|..:..||......                ..||..
Human  1286 VASHINEMQKI--YEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDL 1348

  Fly   385 RSKVFLFDRCLVCTEVRKKRLAYRQHYNWEHVELQRPLDSVSSNANKIINL 435
            ...||:|.|.::        |.|:     |:.:|::.|.|.|..|:...:|
Human  1349 ELTVFVFKRAVI--------LVYK-----ENCKLKKKLPSNSRPAHNSTDL 1386

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.