Protein Alignment CG15611 and Arhgef4

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001355702.1
• Gene: Arhgef4 / 226970
• MGIID: 2442507
• Length: 1855
• Species: Mus musculus
• Alignment Length: 341
• Identity: 73/341 - (21%)
• Similarity: 142/341 - (41%)
• Gaps: 67/341 - (19%)

  Fly   168 IIDELIQTEVNYVNNLKKGMLNY-GQLKDVEDLPEALSGETKQKMLLGNIKEILELHEK--EILP 229
            :|:|::.||.:|:.:|:.....| .|.:..||    :..|.:.:.:.|||::|....:.  :.|.
Mouse  1453 VINEILSTERDYIKHLRDICEGYVRQCRKRED----MFSEEQLRTIFGNIEDIYRCQKAFVKALE 1513

  Fly   230 LMLRNQR----DLKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRLWLQTY--------Q 282
            .....:|    :|...|.|..|.|:..|.||    .....:.::|.:..:|....|        |
Mouse  1514 QKFNTERPHLSELGACFLEHQADFQIYSEYC----NNHPNACVELSRLTKLSKYVYFFEACRLLQ 1574

  Fly   283 TQIKDKLGIDSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTA------VCKLETRMRRAL 341
            ..|  .:.:|.||:.|:|::.:|||.|.:.:...:......|.|..|      |.:|....:|.|
Mouse  1575 RMI--DISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKNVEAALHAMKNVAQLINERKRRL 1637

  Fly   342 DVVNQ-AEEIPNIEE-------LNELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLFDRCLV-C 397
            :.::: |:...:||:       :...:::..|...|.|:      |..:..:...|||||.|: |
Mouse  1638 ENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQ------PQARSQQRMFFLFDRQLIYC 1696

  Fly   398 TE--VRKKRLAYRQHYNWEHVEL-------QRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEY 453
            .:  :|:..|.|:...:.:.:|:       .|.|.....||.::.            .|:..:.:
Mouse  1697 KKDLLRRDVLYYKGRLDMDDLEVVDVEDGKDRDLHVSVKNAFRLY------------CGTTGDSH 1749

  Fly   454 SFMAAEASVVKQWLQA 469
            ...|.:....::||:|
Mouse  1750 LLCARKPEQKQRWLKA 1765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	39/159 (25%)
Arhgef4	NP_001355702.1	SH3_ASEF	1344..1416	CDD:212906
		RhoGEF	1450..1631	CDD:238091	44/187 (24%)
		PH_Collybistin_ASEF	1637..1776	CDD:269931	28/147 (19%)