Protein Alignment CG15611 and trio

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_061507587.1
• Gene: trio / 1276778
• VectorBaseID: AGAMI1_007407
• Length: 2372
• Species: Anopheles gambiae
• Alignment Length: 536
• Identity: 109/536 - (20%)
• Similarity: 204/536 - (38%)
• Gaps: 181/536 - (33%)

  Fly    55 KECPLLESQSPSSPI---------ATTLPKS----QASSNGKLEKQISL---------------- 90
            :|...:|...|..||         |:.:|.|    .|.|..|:.|.:||
Mosquito  1880 EEATAIELPPPMKPIQDTASALSGASVVPSSAEDAAAGSTNKITKAMSLKSLEEPVGAQPPADLA 1944

  Fly    91 ---------------LDSDSGISLSSINTCSTTAA--------NSSPTYRAPNGFHSFPSHTLSF 132
                           ||:|.|...||.::.:...|        :||....|.||     .||::.
Mosquito  1945 EIEQFVKAKVESLKYLDNDGGGGGSSSSSAAAALAMGLMVGDGSSSSGTMALNG-----GHTIAK 2004

  Fly   133 ETLGDEYHEDE---DTLSLENLFPCDQTEIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLK 194
            ..:..::.|:|   |||:.|.   |.:..:   :|.::.:.||:.||..|||:|.: ::| |.:.
Mosquito  2005 PAISPQFSENEAADDTLTEEQ---CIEDIL---RKRNYALRELLTTEEAYVNDLSQ-IVN-GYIA 2061

  Fly   195 DVED------LPEALSGETKQKMLLGNIKEILELHEKEIL--------------PLMLRNQRDLK 239
            ::.:      :|:.|.| .|::|:.|||:.|.|.|....|              ||:.|::|.|
Mosquito  2062 EIRNPASTVLIPDDLKG-GKERMVFGNIEAIYEWHRDHFLKALQKCLQNPYELGPLIKRSERKL- 2124

  Fly   240 GLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRLWLQTYQTQIKDKLGIDSFLVQPIQRLTR 304
                           :.||.:...|..|..:.|::..:....:.::|.||.:...|::|:||:.:
Mosquito  2125 ---------------HMYVVYCQNKPVSEHIVQEHMSYFDELRLKLKYKLCLGDMLIKPVQRIMK 2174

  Fly   305 YPLLLQQFISEFYKSGISCKPVLTAVCKLETRMRRALDVVNQAEEIPNIEELNEL---------D 360
            |.|||:..:....::|::                         ||:|.::|...:         |
Mosquito  2175 YELLLKDILKHTLRAGLT-------------------------EEVPGLKEAMHIMQVVPKAAND 2214

  Fly   361 VLQLGNFRR----------------------ATEFDAQHFPTRKKYRSKVFLFDRCLVCTEVRKK 403
            ::.:|..::                      |:..|...:.::|.....||||::.::..|:..|
Mosquito  2215 MMDVGRLQKFEGKITTQGKLLLHGPLYCVEGASSSDKNSYNSQKPKELHVFLFEQNIIFAEIVGK 2279

  Fly   404 R-------LAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFM--AAE 459
            :       ..|:.|.....:.||...|..:.|...:           .|:..:|...|::  |..
Mosquito  2280 KTQFTSPNYIYKAHIQVNKMTLQDLSDQTNGNRFSL-----------CSIDPQRSSLSYICTAPT 2333

  Fly   460 ASVVKQWLQATHKIIE 475
            ..:..:||...|:|::
Mosquito  2334 PELHSEWLNTIHEILK 2349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	43/165 (26%)
trio	XP_061507587.1	None