Protein Alignment CG15611 and arhgef4

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_004917856.1
• Gene: arhgef4 / 100487089
• XenbaseID: XB-GENE-960463
• Length: 1808
• Species: Xenopus tropicalis
• Alignment Length: 341
• Identity: 78/341 - (22%)
• Similarity: 148/341 - (43%)
• Gaps: 67/341 - (19%)

  Fly   168 IIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIKEILELHEKEILPLML 232
            :|:|::.||.:|:.:||.  :..|.:|......:..: |.:...:.|||:||.:..:|.:..|..
 Frog  1404 VINEILNTEKHYIKHLKD--ICEGYIKQCRKRDDMFT-EDQLWTIFGNIEEIYKFQKKFLKTLEK 1465

  Fly   233 RNQRD------LKGLFDEFAAHFEKNSFYC---------YVSFTMGKKSSMQLRQDNRLWLQTYQ 282
            |..:|      :...|.|:...|:..|.||         ....|..||           ::..::
 Frog  1466 RINKDSPHLSEIGSCFLEYQTDFQIYSEYCNNHPNACTELSKLTKVKK-----------YVHFFE 1519

  Fly   283 T----QIKDKLGIDSFLVQPIQRLTRYPLLLQQ---FISEFYKSGISCKPVLTA---VCKLETRM 337
            |    |....:.:|.||:.|:|::.:|||.|.:   :.:..::...:.:..|.|   |.:|....
 Frog  1520 TCRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTNSQHRDYTNVEAALDAMKNVARLINER 1584

  Fly   338 RRALDVVNQ-AEEIPNIEELNELDVLQLGNFRRATEF-------DAQHFPTRKKYRSKVFLFDRC 394
            :|.|:.::: |....:||:....|:|     .|::|.       ...|...:.:.|. .||||..
 Frog  1585 KRRLENIDKIAHWQSSIEDWEGEDIL-----ARSSELIHSGELTKISHLQPKGQQRI-FFLFDHQ 1643

  Fly   395 LV-CTE--VRKKRLAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQE---EGGSSVGSKREEY 453
            :| |.:  :|:..|.|:...:.:.:|:.    :|....:|..|:.||..   :|..|    .|.:
 Frog  1644 IVFCKKDLLRRDILYYKGKIDMDDMEVL----NVEDGKDKDFNITVKNAFKLQGKVS----EEIH 1700

  Fly   454 SFMAAEASVVKQWLQA 469
            .|:|.:....::||||
 Frog  1701 LFLAKKPEHKQRWLQA 1716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	39/166 (23%)
arhgef4	XP_004917856.1	SH3_ASEF	1291..1363	CDD:212906
		RhoGEF	1404..1583	CDD:214619	43/192 (22%)
		PH_Collybistin_ASEF	1588..1727	CDD:269931	34/143 (24%)