Protein Alignment CG15611 and mcf2l2

DIOPT Version :10

• Sequence 1: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_073772492.1
• Gene: mcf2l2 / 100149630
• ZFINID: ZDB-GENE-100812-1
• Length: 1284
• Species: Danio rerio
• Alignment Length: 485
• Identity: 104/485 - (21%)
• Similarity: 186/485 - (38%)
• Gaps: 109/485 - (22%)

  Fly    50 DKAPAKECPLLESQSPSSPIATTLPKSQAS---SNGKLEKQISLLDSDSGISLSSINTCSTTAAN 111
            :.:|.:..|.:...:|.:....|...|..:   |:.:|.|:.::..:..||.:..::
Zfish   569 ESSPKRPSPKIPHPTPPTSHRKTTDNSSTNRQPSDAELAKRKNIRKAKGGIKIEVMH-------- 625

  Fly   112 SSPTYRAPNGFHSFPSHTLSFETLGDEYHEDEDTLSLENLFPCDQTEIYASKKISFIIDELIQTE 176
                    .|.....||.|                 :.|     :||...|.:.|.|::|||:||
Zfish   626 --------EGGQGGSSHIL-----------------MNN-----ETEESLSNRRSHIMNELIETE 660

  Fly   177 VNYVNNLKKGMLNYGQLKDVEDL----PEALSGETKQKMLLGNIKEILELHEKEILPLMLRNQRD 237
            ..||..|:..:..|....|..:|    |.:|  |.|:::|.||:.||.:.|:|..|. .|.|..:
Zfish   661 RLYVEELQSIIEGYAAALDDPELIYLIPPSL--ENKKEVLFGNLPEIYQFHQKIFLK-ELENSAE 722

  Fly   238 ---------LKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQL-RQ-DNRLWLQTYQTQIKDKLGI 291
                     ||          .|.....|..:...|..|..| || .:.::.|..|.::..||.:
Zfish   723 KPELVGTCFLK----------RKEELQIYEKYCQNKPRSEALWRQCGDSMFFQECQKRLDHKLSL 777

  Fly   292 DSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTAVCKLETRMRRALDVVNQAEE------I 350
            |::|::|:||:|:|.|:|::.        :.|........:||......||::....:      |
Zfish   778 DAYLLKPVQRITKYQLMLKEM--------LKCSKNPEGTAELEEAQATVLDIIKSVNDSMHQIAI 834

  Fly   351 PNIE-ELNEL-DVLQLGNFRRATEFDAQHFPTRKKYRSK-----VFLFDRCLVCTEVRKKRLAYR 408
            ...| .||:| .:|..|:|...|:....|...:...|.|     :||:.:.::..:.|::.....
Zfish   835 TGFEGSLNDLGKLLMQGSFNVWTDHKKGHSKVKDLARFKPMQRHLFLYHKMILFCKKREEMTDGH 899

  Fly   409 Q---HYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFMAAEASVVKQWLQAT 470
            :   .|:::| .|:.....::.|....|........|      :.|.|...|....|...|:...
Zfish   900 EKSPSYSFKH-SLKMGSVGITENVKGDIKKFEIWYNG------REEVYIIQAPSMDVKNTWVSEI 957

  Fly   471 HKI----IEIAR-----NEHARRNTFSLPM 491
            .|:    :|..|     ::....|.:..||
Zfish   958 RKVLTSQLEACREASQLHQKITENIYHAPM 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	48/160 (30%)
mcf2l2	XP_073772492.1	None