Protein Alignment CG30456 and si:dkey-91i10.2

DIOPT Version :9

• Sequence 1: NP_611188.3
• Gene: CG30456 / 36929
• FlyBaseID: FBgn0050456
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_005167625.1
• Gene: si:dkey-91i10.2 / 555224
• ZFINID: ZDB-GENE-050208-441
• Length: 1121
• Species: Danio rerio
• Alignment Length: 608
• Identity: 117/608 - (19%)
• Similarity: 212/608 - (34%)
• Gaps: 187/608 - (30%)

  Fly    77 SDTDSSYRHRSLLKMHEAESVGGLGTESTPESPMSPQTPDPALLDV--RQKVHRFEAFRTNICFI 139
            |.:|::|        ..||||     ::..|..:.|...||...|.  |:::....|....:...
Zfish   555 SSSDAAY--------ELAESV-----KAQRECRLRPHYSDPMPADATKRKQLEMKIAAAARLHIH 606

  Fly   140 KQERHSLK-LLENRRHPSFEDQSEDHHTPPATPPRRIRLPGLGSRGSS--RSSSIPSFQAGIHEV 201
            :::|.:.. ....|..|..|::|.                |||.|.|:  |.|::.|..|....|
Zfish   607 RRDRDTAAGTARGRSEPRGEERSR----------------GLGVRRSAQHRWSTVSSLSADSGVV 655

  Fly   202 RSEDEVDQISDFETDSHTAAEEYLVVD---------TTSEVVPSEEVADSKVDQQQVQRSISADQ 257
            ...||.:...:.....|:|..|...||         :....:||....|       ||:......
Zfish   656 GWSDEREDEEEPRRARHSAGAEVERVDSGIGHGLARSWRRPLPSLRTWD-------VQQPCPDCG 713

  Fly   258 SKEALTLPLKMRNDFPRNYRSTPRRKTEIIGTTNEHLVGKFHSVYQPKDEEEEVEIELRDKSDKC 322
            .||                              ..|..|......:.:.|.:|.
Zfish   714 HKE------------------------------GAHGEGMCERCSKLRTERKEA----------- 737

  Fly   323 VHPILEELIKTEEAYVNNL-------FTGIENYGNIFQRKDLPLGLRGKKYDLFGNIEQIAEFHR 380
                :.|.:.||.:|..:|       :..:::.| :...:.|.:        :|.|::::.:.:
Zfish   738 ----ILEFLNTESSYGEDLRIIKEEFYCPMQSAG-LLTAEQLAV--------VFSNVQELIDVN- 788

  Fly   381 DEFLPMLQRNRRDLKRLFDE-------------FLQFLDQ-HCFYGY---------VIFTMNKQK 422
            ::|...||.:   :.:.||:             ||:|::. ..|..|         ::.|:.|:|
Zfish   789 EKFTEHLQDS---IDQAFDQGDEDLQAVCIGEIFLEFVNMLPAFQTYCLQQSTSVNMLNTLEKEK 850

  Fly   423 SLK--LCDLYKNYFTSIRLERDDKLGINSFLVQPIQRMARYPLLLTQFINTFFKNRDIVMKP-LI 484
            .|.  ..|:.:|..|::|     ::.:.|||:.|:||:.:|||||::....  .|......| |.
Zfish   851 ELLRIFLDVSQNDNTALR-----RMNLRSFLMAPLQRVTKYPLLLSRISKA--TNECHPDYPRLK 908

  Fly   485 ESCCRLEKRLRALLTTTNES------------------EIINDIVDCHEFNVYYQGKFRKVNEF- 530
            |:..|:|..|..:...|.:.                  |:||  ::..|.::...|..|:...|
Zfish   909 EAKSRVESHLEHINMKTKQEGTATWSLRSFRRDSRKNREVIN--IEMRELSMKMVGWARESTRFI 971

  Fly   531 --------QVLDHK-LKRSYRSKVF------IFDKCIIYTEIKGKNLLFHGRYPCEHIGISAKTK 580
                    |..|.: ||:..:|..|      :..:.:..|:......|.......:.:.:..|.|
Zfish   972 MEGPLQLAQPADGQWLKKGSKSLKFQNVQSLLMVRTLRATDAVPDGSLESSEAVQDGVLVLIKDK 1036

  Fly   581 S---FTLYYERRKQQECEFTADP 600
            |   ||:..|..:...|..:.||
Zfish  1037 SSGKFTVLREPIRLANCVVSVDP 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30456	NP_611188.3	RhoGEF	326..470	CDD:279015	38/175 (22%)
si:dkey-91i10.2	XP_005167625.1	RhoGEF	737..922	CDD:279015	45/219 (21%)
		PH	<1025..1094	CDD:214574	9/35 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960