Protein Alignment CG46491 and CG15611

DIOPT Version :10

• Sequence 1: NP_611188.3
• Gene: CG46491 / 36929
• FlyBaseID: FBgn0287631
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: NP_611189.2
• Gene: CG15611 / 36930
• FlyBaseID: FBgn0034194
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 487
• Identity: 154/487 - (31%)
• Similarity: 238/487 - (48%)
• Gaps: 73/487 - (14%)

  Fly   204 EDEVDQISDFETDSHTAAEEYLVVDTTSEVVPSEEVADSKVDQQ-----QVQRSISADQSKEALT 263
            :|..|.....:......|:|..::::.|   ||..:|.:....|     ::::.||...|...::
  Fly    37 DDNADNGKSIDVVDKAPAKECPLLESQS---PSSPIATTLPKSQASSNGKLEKQISLLDSDSGIS 98

  Fly   264 L------PLKMRND-----FPRNYRSTPRRKTEIIGTTNEHLVGKFHSVYQPKDEEEEVEIELRD 317
            |      .....|.     .|..:.|.|......     |.|..::|      ::|:.:.:|...
  Fly    99 LSSINTCSTTAANSSPTYRAPNGFHSFPSHTLSF-----ETLGDEYH------EDEDTLSLENLF 152

  Fly   318 KSD-------KCVHPILEELIKTEEAYVNNLFTGIENYGNIFQRKDLPLGLRG--KKYDLFGNIE 373
            ..|       |.:..|::|||:||..|||||..|:.|||.:...:|||..|.|  |:..|.|||:
  Fly   153 PCDQTEIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIK 217

  Fly   374 QIAEFHRDEFLPMLQRNRRDLKRLFDEFLQFLDQHCFYGYVIFTMNKQKSLKLCDLYKNYFTSIR 438
            :|.|.|..|.||::.||:||||.|||||....:::.||.||.|||.|:.|::|....:.:..:.:
  Fly   218 EILELHEKEILPLMLRNQRDLKGLFDEFAAHFEKNSFYCYVSFTMGKKSSMQLRQDNRLWLQTYQ 282

  Fly   439 LERDDKLGINSFLVQPIQRMARYPLLLTQFINTFFKNRDIVMKPLIESCCRLEKRLRALLTTTNE 503
            .:..|||||:|||||||||:.||||||.|||:.|:|: .|..||::.:.|:||.|:|..|...|:
  Fly   283 TQIKDKLGIDSFLVQPIQRLTRYPLLLQQFISEFYKS-GISCKPVLTAVCKLETRMRRALDVVNQ 346

  Fly   504 SEIINDIVDCHEFNVYYQGKFRKVNEFQVLDHKLKRSYRSKVFIFDKCIIYTEIKGKNLLFHGRY 568
            :|.|.:|.:.:|.:|...|.||:..||.......::.||||||:||:|::.||::.|.|.:...|
  Fly   347 AEEIPNIEELNELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLFDRCLVCTEVRKKRLAYRQHY 411

  Fly   569 PCEHIGI--------SAKTKSFTLYYERR--------KQQECEF-TADPVQIAIWLDLIRDMINN 616
            ..||:.:        |...|...|..::.        |::|..| .|:...:..||.....:|..
  Fly   412 NWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFMAAEASVVKQWLQATHKIIEI 476

  Fly   617 YANEERQKLQERYSRENDHLHRKAPSFSLYRD 648
            ..||                |.:..:|||..|
  Fly   477 ARNE----------------HARRNTFSLPMD 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46491	NP_611188.3	RhoGEF	326..469	CDD:459876	73/144 (51%)
		ROM1	<438..>660	CDD:227709	78/228 (34%)
CG15611	NP_611189.2	RhoGEF	167..313	CDD:470622	73/145 (50%)