Protein Alignment CG30456 and Plekhg4

DIOPT Version :9

• Sequence 1: NP_611188.3
• Gene: CG30456 / 36929
• FlyBaseID: FBgn0050456
• Length: 682
• Species: Drosophila melanogaster
• Sequence 2: XP_038954139.1
• Gene: Plekhg4 / 307796
• RGDID: 1310790
• Length: 1231
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 117/490 - (23%)
• Similarity: 199/490 - (40%)
• Gaps: 121/490 - (24%)

  Fly   253 ISADQSKEALTLPLKMRNDFPRNYRSTP--------RRKTEIIGTTNEHL---VGKFHSVYQPKD 306
            ::.||.:||...|..|.:......|..|        |:.........:||   ..:.|......|
  Rat   653 LALDQKREAALKPQSMNSTATLYVRRAPAIPTIPPLRKSYSFDQNLGKHLGDASNRGHCAATVTD 717

  Fly   307 -EEEEVEIELRDKSDKCV--------------HPILEELIKTEEAYVNNLFTGIENYGNIFQRKD 356
             ...|....:|.:|...|              ..:|.|::.||..||..|...|:||.....|.|
  Rat   718 CHRPEARGGIRPRSSPSVPLSGSSDFRSPNRLQLVLAEMVATEREYVRALDYTIQNYFPELDRSD 782

  Fly   357 LPLGLRGKKYDLFGNIEQIAEFHRDEFLPMLQRNRRDLKRLFDEFLQFLDQHCFYGYVIFTMNKQ 421
            :|.||||::..||||:|::.:||...||..|:...|...|:...||:...|  |..|.:::.||.
  Rat   783 VPQGLRGQRAHLFGNLEKLRDFHFHFFLRELEACTRHPPRVAHAFLRHRVQ--FGMYALYSKNKP 845

  Fly   422 KSLKLCDLY-KNYFTSIRLERDDKLGINSFLVQPIQRMARYPLLLTQFINTFFKNRDIVMKPLIE 485
            :|..|...| ..:|...:....|.|.:.|:|::|||||::|.|||.:               |..
  Rat   846 RSDALMSNYGHTFFKEKQQALGDHLDLASYLLKPIQRMSKYALLLQE---------------LAR 895

  Fly   486 SCCRLEKRLRAL----------LTTTNESEIINDIVDCHEFNVYYQGKFRKVNEFQVL--DHKLK 538
            :|....:.|.||          |...|:...::.|..| :.|:..||:..:.:||.|.  .||..
  Rat   896 ACGGPAQELGALQAAQSLVHFQLRHGNDLLAMDAIQGC-DVNLKEQGQLVRQDEFTVRAGHHKSC 959

  Fly   539 RSYRSKVFIFDKCIIYTEIK----GKNLLFHGR-YPCEHIGIS---AKTK-SFTLYYERRKQQEC 594
            |    :||:|::.:::::.:    |.::..:.| :....:|::   .::| .|.:::.|||.::.
  Rat   960 R----RVFLFEELLLFSKPRRGPAGVDIFTYKRSFKMADLGLTECCGESKLRFEIWFRRRKARDL 1020

  Fly   595 ------------EFTADPVQIAIWLDLIRDMINNYANEERQKLQERYSRENDHLHRKAPSFSLYR 647
                        .:||| :...:|    |..::|    :..::.|..|
  Rat  1021 FVLQASDVATKQAWTAD-ISRLLW----RQAVHN----KEVRMAEMAS----------------- 1059

  Fly   648 DSNRFSSDSGIGN--IW-IMPKADEDTISNRTTWY 679
                    .|:||  .| |.|  .|:.|::|...|
  Rat  1060 --------MGVGNKAFWDIAP--SEEAINDRNINY 1084

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30456	NP_611188.3	RhoGEF	326..470	CDD:279015	53/144 (37%)
Plekhg4	XP_038954139.1	SPEC	463..>614	CDD:413338
		RhoGEF	749..915	CDD:238091	58/182 (32%)
		PH_puratrophin-1	915..1050	CDD:270062	30/148 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910