DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6967 and Mov10l1

DIOPT Version :9

Sequence 1:	NP_611185.3	Gene:	CG6967 / 36922	FlyBaseID:	FBgn0034187	Length:	764	Species:	Drosophila melanogaster
Sequence 2:	XP_006521619.1	Gene:	Mov10l1 / 83456	MGIID:	1891384	Length:	1239	Species:	Mus musculus

Alignment Length:	463	Identity:	163/463 - (35%)
Similarity:	242/463 - (52%)	Gaps:	63/463 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 NAEQLEAVQRIVAGPSTQGPYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIA 315
            |..|..||:||::|.....|||||||||||||.||:||:||:....|.|||||.|.||||.|.:.
Mouse   800 NENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVC 864

  Fly   316 LKLCEYIESNIRLQEHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNC--SKSIYDHI 378
            |:|.|              .|:.:| ..::||                   |:.|  .::|.|.|
Mouse   865 LRLHE--------------SKVLKP-AAMVRV-------------------NATCRFEETIIDAI 895

  Fly   379 KAS--------RIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQ 435
            |..        |..::.||:.| |:.|.|......|..:|||:|:||||.::|||.||. :|:..
Mouse   896 KPYCRDGEDIWRASRFRIIITT-CSSAGLFYQIGVRVGYFTHVFVDEAGQASEPECLIP-LGLIS 958

  Fly   436 TADCHVILSGDHKQLGAVIKSNRAASLGLSRSLMERLLQSDCYKSDEN-----GNYDRNRQMRLC 495
            ..:..::|:||..|||.||||..|.:.||:.|::|||:....|..|||     |.|:.....:|.
Mouse   959 DINGQIVLAGDPMQLGPVIKSRLAMAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLVTKLV 1023

  Fly   496 RNYRSHPQIVRLFNELYYNGELKAQAPAMDVNLAANWSVLTNPQFPIIFQATHGVTNREQNSTSS 560
            :|||||..::.|.:.|:|:.||:..|....|.....|..|....||:||....|...||..|.|.
Mouse  1024 KNYRSHSALLALPSRLFYHRELEVCADPKVVTSLLGWEKLPRKGFPLIFHGVRGNEAREGRSPSW 1088

  Fly   561 YNNLEAEVI---CWYVKRLINDRVVGQEDVGIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQG 622
            ::..||..:   |..:.|.::.: |..:|:|::.||..|.:.:..||::....:::|||||.:||
Mouse  1089 FSPAEAVQVMRYCCLLARSVSSQ-VSSKDIGVITPYRKQVEKIKILLRNVDLTDIKVGSVEEFQG 1152

  Fly   623 REKTIIIASLVKSFTN--------MGFMCNPRRVNVLLSRAKALLILVGNPVTLRHHSDFKFVIN 679
            :|..:|:.|.|:|..:        :||:.|.:|.||.::|.|||||::|||..|.....|..::.
Mouse  1153 QEYLVIVISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIILGNPHVLVRDPCFGALLE 1217

  Fly   680 ECKKHGTY 687
            ....:|.|
Mouse  1218 YSVSNGVY 1225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6967	NP_611185.3	AAA_11	251..456	CDD:289831	81/214 (38%)
		AAA_19	256..323	CDD:289986	39/66 (59%)
		UvrD_C_2	464..665	CDD:304668	72/216 (33%)
Mov10l1	XP_006521619.1	S1-like	119..>161	CDD:373072
		DEXXQc_Mov10L1	798..1027	CDD:350836	98/262 (37%)
		SF1_C_Upf1	1028..1218	CDD:350195	61/190 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831387
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148890at33208
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9180
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.980